Autor(es): Maillane-vanegas, Santiago ; Turi-lynch, Bruna Camilo ; Lira, Fabio Santos De ; Codogno, Jamile Sanches ; Fernandes, Rômulo Araújo ; Lima, Manoel Carlos Spiguel De ; Machado-rodrigues, Aristides ; Kemper, Han C. G.
Data: 2018
Identificador Persistente: http://hdl.handle.net/11449/157925
Origem: Oasisbr
Assunto(s): Aatherosclerosis; insulin resistance; lipid profile; diabetes mellitus
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AbstractAIM The aim of this longitudinal study was to analyze the relationship between sleep disorder and intima-media thickness.METHOD Baseline measurements included carotid intima-media thickness, assessed by an ultrasound device; questionnaires about sleep and other behavioral variables; physical activity was measured by pedometer; body fatness was estimated by Dual-Energy X-ray Absorptiometry; fasting glucose, lipid profile and C-reactive protein were collected.RESULTS The occurrence rate of sleep-related disorders was 47% (95%CI= 37.2%-56.7%). Carotid intima-media thickness was related to symptoms of insomnia (r= 0.328 [0.141 to 0.493]) and, after adjustments for potential confounders, the relationship between carotid intima-media thickness and insomnia remained statistically significant (β= 0.121 [95%CI= 0.017; 0.225]).CONCLUSIONS In young adults, sleep disorder was significantly related to premature increase in carotid intima-media thickness.
Universidade Estadual Paulista
Universidade de Coimbra
University Medical Center
Universidade Estadual Paulista
