Author(s): Bueno, Marina G. ; Iovine, Renata O. [UNESP] ; Torres, Luciana N. ; Catao-Dias, Jose L. ; Pissinatti, Alcides ; Kierulff, Maria C. M. ; Carvalho, Vania M.
Date: 2018
Persistent ID: http://hdl.handle.net/11449/158419
Origin: Oasisbr
Subject(s): Hypermucoviscosity phenotype; Klebsiella pneumoniae; Leontopithecus chrysomelas; translocation
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Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
Fundacao Grupo Boticario de Protecao a Natureza
Lion Tamarin of Brazil Fund
Primate Action Fund
Margot Marsh Foundation
Mohamed bin Zayed Species Conservation Fund
RBO Energia S.A. (Camara de Compensacao Ambiental/Secretaria do Meio Ambiente Rio de Janeiro)
Tropical Forest Conservation Act/Fundo Brasileiro para Biodiversidade (TFCA/FUNBIO)
Klebsiella pneumoniae is an important emerging pathogen in humans, particularly the invasive hypermucoviscosity (HMV) phenotype. In addition, the organism is an important public health concern because of nosocomial infections and antimicrobial resistance. Nonhuman primates in captivity are susceptible to Klebsiella, particularly when a stress factor is involved. Infections vary depending on the species but can cause significant morbidity and mortality in these animals. The objective of this study was to describe a case of bronchopneumonia and bacteremia caused by Klebsiella pneumoniae in a free-ranging golden-headed lion tamarin (Leontopithecus chrysomelas) caught and maintained in quarantine during a translocation program for conservation purposes. An adult male, that had showed emaciation and apathy, was clinically examined and, despite being provided supportive therapy, died 2 days after onset of clinical signs. At postmortem examination, generalized bilateral pneumonia and pericarditis were observed. Tissue samples were fixed in 10% formalin for histology, and pulmonary tissues and cardiac blood were collected for microbiologic diagnostic procedures. Bacteria that were shown to be HMV K. pneumoniae subsp. pneumoniae strains were isolated from the pulmonary fluids and cardiac blood in pure cultures. Severe bronchopneumonia was the main pathological finding. The consequences of the confirmed presence of the HMV phenotype of K. pneumoniae subsp. pneumoniae in this wildlife species for human, animal, and ecosystem health should be determined. These results demonstrate the importance of quarantine and potential pathogen screening during wildlife translocation procedures.
Pri Matas Biodivers Conservat Inst, Belo Horizonte, MG, Brazil
Univ Estadual Paulista, Inst Hlth Sci, Mol & Cell Biol Lab, Sao Paulo, Brazil
Univ Sao Paulo, Dept Pathol, Sch Vet Med & Anim Sci, Lab Wildlife Comparat Pathol,LAPCOM, Sao Paulo, Brazil
Rio de Janeiro Primatol Ctr CPRJ INEA, Rio De Janeiro, Brazil
Serra dos Orgaos Univ UNIFESO, Rio De Janeiro, Brazil
Univ Fed Espirito Santo, Postgrad Program Trop Biodivers, Sao Mateus, ES, Brazil
Univ Estadual Paulista, Inst Hlth Sci, Mol & Cell Biol Lab, Sao Paulo, Brazil
FAPESP: 2011/08149-8
