Autor(es):
Costa, Danielle Nunes Carneiro Castro ; Blangiardo, Marta ; Rodas, Lilian Aparecida Colebrusco ; Nunes, Caris Maroni [UNESP] ; Hiramoto, Roberto Mitsuyoshi ; Tolezano, José Eduardo ; Bonfietti, Lucas Xavier ; Bermudi, Patricia Marques Moralejo ; Cipriano, Rafael Silva ; Cardoso, Graziela Cândido Diniz ; Codeço, Cláudia Torres ; Chiaravalloti-Neto, Francisco
Data: 2018
Identificador Persistente: http://hdl.handle.net/11449/176740
Origem: Oasisbr
Assunto(s): Brazil; Cross-sectional study; Dogs; Geostatistical analysis; Visceral leishmaniasis
Descrição
Made available in DSpace on 2018-12-11T17:22:17Z (GMT). No. of bitstreams: 0 Previous issue date: 2018-07-31
Background: The incidence of visceral leishmaniasis (VL), one of the most important neglected diseases worldwide, is increasing in Brazil. The objectives of this study were to determine the canine VL (CanL) seroprevalence in an urban area of Araçatuba municipality and to evaluate its relationship with the characteristics of dogs and their owners. Results: The CanL seroprevalence in the study area was 0.081 (95% credible interval [CI]: 0.068-0.096). The following covariates/categories were positively associated with the occurrence of a seropositive dog: more than 10 dogs that had lived in the house (odds ratio [OR]=2.36; 95% CI: 1.03-5.43) (baseline: 0-10 dogs); house with dogs that previously died of VL (OR=4.85; 95% CI: 2.65-8.86) or died of causes other than old age (OR=2.26; 95% CI: 1.12-4.46) (baseline: natural or no deaths); dogs that spent the day in a sheltered backyard (OR=2.14; 95% CI: 1.05-4.40); dogs that spent the day in an unsheltered backyard or the street (OR=2.67; 95% CI: 1.28-5.57) (baseline: inside home). Spatial dependence among observations occurred within about 45.7m. Conclusions: The number of dogs that had lived in the house, previous deaths by VL or other cause, and the place the dog stayed during the day were associated with the occurrence of a VL seropositive dog. The short-distance spatial dependence could be related to the vector characteristics, producing a local neighbourhood VL transmission pattern. The geostatistical approach in a Bayesian context using integrated nested Laplace approximation (INLA) allowed to identify the covariates associated with VL, including its spatially dependent transmission pattern.
USP Programa de Pós-graduação em Saúde Pública Faculdade de Saúde Pública, Avenida Doutor Arnaldo 715
Imperial College MRC-PHE Centre for Environment and Health Department of Epidemiology and Biostatistics, St. Mary's Campus, Norfolk Place
Serviço Regional 9 Superintendência de Controle de Endemias, Rua Minas Gerais, 135
Unesp Laboratório de Bioquimica e Biologia Molecular Departamento de Apoio Producao e Saude Animal Faculdade de Medicina Veterinária de Araçatuba, Rua Clóvis Pestana 793
Núcleo de Parasitoses Sistêmicas Instituto Adolfo Lutz, Av. Doutor Arnaldo 355, 8o. Andar
Cento de Laboratório Regional I Araçatuba Instituto Adolfo Lutz, R. Minas Gerais 135
Centro de Controle de Zoonozes, Rua Doutor Luiz de Almeida 145
Fundação Oswaldo Cruz Programa de Computação Científica, Avenida Brasil 4365, Antiga Residência Oficial
Universidade de São Paulo (USP) Departamento de Epidemiologia Faculdade de Saúde Pública, Avenida Doutor Arnaldo 715
Unesp Laboratório de Bioquimica e Biologia Molecular Departamento de Apoio Producao e Saude Animal Faculdade de Medicina Veterinária de Araçatuba, Rua Clóvis Pestana 793
