Author(s):
Lara, Bruna Rossini ; Araujo Melo, Milena Barrocali de ; Paula, Claudete Rodrigues ; Arnoni, Mariana Volpe ; Simoes, Cirilo Cesar Naozuka ; Nakano, Shirley ; Richini-Pereira, Virginia Bodelao ; Garces, Hans Garcia [UNESP] ; Maciel da Silva, Bosco Christiano ; Anversa, Lais ; Silva, Eriques Gonsalves ; Auler, Marcos Ereno ; Oliveira dos Santos, Rennan Luiz ; Ruiz, Luciana da Silva
Date: 2019
Persistent ID: http://hdl.handle.net/11449/186008
Origin: Oasisbr
Subject(s): Antifungals; biofilm; cancer; enzymes; nosocomial infection; skin lesion; Tremellomycetes; yeasts
Description
Made available in DSpace on 2019-10-04T12:40:28Z (GMT). No. of bitstreams: 0 Previous issue date: 2019-08-05
Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
This is the first report of the yeast Apiotrichum veenhuisii (formerly Trichosporon veenhuisii) causing disease in humans; its virulence and in vitro behavior against antifungals were also studied. The sample was isolated from biopsy fragments of disseminated lesions on the skin of a pediatric patient with acute myeloid leukemia. The studied virulence factors evidenced that the strain tested negative for secretion of the enzymes proteinase, phospholipase, and hemolysin. The isolate was characterized as low biofilm producer. Except for amphotericin B and voriconazole, the sample presented high minimum inhibitory concentration values against azole and echinocandins.
Adolfo Lutz Inst, CLR 2, Nucleo Ciencias Biomed, Bauru, SP, Brazil
Univ Sao Paulo, Fac Odontol, Sao Paulo, SP, Brazil
Hosp Infantil Darcy Vargas, Sao Paulo, SP, Brazil
Univ Estadual Paulista, Dept Microbiol & Imunol, Botucatu, SP, Brazil
Univ Sao Paulo, Fac Med, Sao Paulo, SP, Brazil
Adolfo Lutz Inst, Nucleo Ciencias Quim & Bromatol, Bauru, SP, Brazil
Univ Estadual Ctr Oeste Parana, Guarapuava, Parana, Brazil
Univ Estadual Paulista, Dept Microbiol & Imunol, Botucatu, SP, Brazil
