Author(s): dos Santos Souza, Éder [UNESP] ; Fernandes, Richard Perosa [UNESP] ; Galvão, Cleber ; de Paiva, Vinícius Fernandes ; da Rosa, João Aristeu [UNESP]
Date: 2019
Persistent ID: http://hdl.handle.net/11449/187874
Origin: Oasisbr
Subject(s): Cavernicola; MALDI TOF; Mass spectrometry
Made available in DSpace on 2019-10-06T15:49:56Z (GMT). No. of bitstreams: 0 Previous issue date: 2019-10-01
Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
The blood-sucking insects of the subfamily Triatominae are vectors of Chagas disease, the most impairing protozoan parasitic infection in Latin America. Among the five tribes known in the subfamily, one of the least studied is Cavernicolini. It has only two species within Cavernicola genus (Barber, 1937), little is known about the biochemistry of the species of this genus, therefore, using MALDI-TOF MS we provide a better understanding of the two species and differentiates them. The distinction was made by the different spectral profile of the species, where C. lenti presents unique signals in many regions, while the C. pilosa shows high-intensity signals and m/z in high bands. The application of digital mass spectrometry combined with chemometric methods was able to accurately distinguish two species of the genus Cavernicola.
Faculdade de Ciencias Farmacêuticas Universidade Estadual Paulista “Julio de Mesquita Filho” (UNESP)
Universidade Estadual Paulista “Júlio de Mesquita Filho” (UNESP) Instituto de Química
Laboratorio Nacional e Internacional de Referência em Taxonomia de Triatomíneos Instituto Oswaldo Cruz FIOCRUZ
Instituto de Biologia Universidade Estadual de Campinas (UNICAMP)
Faculdade de Ciencias Farmacêuticas Universidade Estadual Paulista “Julio de Mesquita Filho” (UNESP)
Universidade Estadual Paulista “Júlio de Mesquita Filho” (UNESP) Instituto de Química
