Author(s): Edalati, Parisa ; Floriano, Ricardo ; Tang, Yongpeng ; Mohammadi, Abbas ; Pereira, Karina Danielle [UNESP] ; Luchessi, Augusto Ducati [UNESP] ; Edalati, Kaveh
Date: 2020
Persistent ID: http://hdl.handle.net/11449/198698
Origin: Oasisbr
Subject(s): Biomaterials; CALPHAD (calculation of phase diagram) method; High-entropy alloys (HEAs); Lattice softening; Phase transformation; Severe plastic deformation (SPD)
Made available in DSpace on 2020-12-12T01:19:41Z (GMT). No. of bitstreams: 0 Previous issue date: 2020-07-01
Ministry of Education, Culture, Sports, Science and Technology
Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
Instituto Serrapilheira
Despite significant studies on mechanical properties of high-entropy alloys (HEAs), there have been limited attempts to examine the biocompatibility of these alloys. In this study, a lattice-softened high-entropy alloy TiAlFeCoNi with ultrahigh hardness (examined by Vickers method), low elastic modulus (examined by nanoindentation) and superior activity for cell proliferation/viability/cytotoxicity (examined by MTT assay) was developed by employing imperial data and thermodynamic calculations. The designated alloy after casting was processed further by high-pressure torsion (HPT) to improve its hardness via the introduction of nanograins, dislocations and order-disorder transformation. The TiAlFeCoNi alloy with the L21-BCC crystal structure exhibited 170–580% higher hardness and 260–1020% better cellular metabolic activity compared to titanium and Ti-6Al-7Nb biomaterials, suggesting the high potential of HEAs for future biomedical applications.
WPI International Institute for Carbon-Neutral Energy Research (WPI-I2CNER) Kyushu University
School of Applied Sciences University of Campinas (UNICAMP)
Institute of Biosciences São Paulo State University (UNESP)
Institute of Biosciences São Paulo State University (UNESP)
Ministry of Education, Culture, Sports, Science and Technology: 19H05176
FAPESP: 2013/23620-4
FAPESP: 2018/15968-4
Instituto Serrapilheira: Serra-1709-17362
