Author(s):
Costa, Raphael C. ; Souza, João G.S. ; Cordeiro, Jairo M. ; Bertolini, Martinna ; de Avila, Erica D. [UNESP] ; Landers, Richard ; Rangel, Elidiane C. [UNESP] ; Fortulan, Carlos A. ; Retamal-Valdes, Belén ; da Cruz, Nilson C. [UNESP] ; Feres, Magda ; Barão, Valentim A.R.
Date: 2020
Persistent ID: http://hdl.handle.net/11449/200708
Origin: Oasisbr
Subject(s): Bioactive coatings; Bioactive glass; Biofilms; Biomaterials; Corrosion; Dental implant; Plasma electrolytic oxidation; Proteins; Surface modification; Titanium
Description
Made available in DSpace on 2020-12-12T02:13:53Z (GMT). No. of bitstreams: 0 Previous issue date: 2020-11-01
Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
Centro Nacional de Pesquisa em Energia e Materiais
Laboratório Nacional de Nanotecnologia
Universidade Estadual de Campinas
Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
Fundo de Apoio ao Ensino, à Pesquisa e Extensão, Universidade Estadual de Campinas
Hypothesis: Although bioactive glass (BG) particle coatings were previously developed by different methods, poor particle adhesion to surfaces and reduced biological effects because of glass crystallization have limited their biomedical applications. To overcome this problem, we have untangled, for the first time, plasma electrolytic oxidation (PEO) as a new pathway for the synthesis of bioactive glass-based coating (PEO-BG) on titanium (Ti) materials. Experiments: Electrolyte solution with bioactive elements (Na2SiO3-5H2O, C4H6O4Ca, NaNO3, and C3H7Na2O6P) was used as a precursor source to obtain a 45S5 bioglass-like composition on a Ti surface by PEO. Subsequently, the PEO-BG coating was investigated with respect to its surface, mechanical, tribological, electrochemical, microbiological, and biological properties, compared with those of machined and sandblasted/acid-etched control surfaces. Findings: PEO treatment produced a coating with complex surface topography, Ti crystalline phases, superhydrophilic status, chemical composition, and oxide layer similar to that of 45S5-BG (~45.0Si, 24.5 Ca, 24.5Na, 6.0P w/v%). PEO-BG enhanced Ti mechanical and tribological properties with higher corrosion resistance. Furthermore, PEO-BG had a positive influence in polymicrobial biofilms, by reducing pathogenic bacterial associated with biofilm-related infections. PEO-BG also showed higher adsorption of blood plasma proteins without cytotoxic effects on human cells, and thus may be considered a promising biocompatible approach for biomedical implants.
Department of Prosthodontics and Periodontology Piracicaba Dental School University of Campinas (UNICAMP), Av. Limeira, 901
Oral Health and Diagnostic Sciences Department Division of Periodontology University of Connecticut School of Dental Medicine, 263 Farmington Avenue
Department of Dental Materials and Prosthodontics School of Dentistry at Araraquara São Paulo State University (UNESP), R. Humaitá, 1680
Institute of Physics Gleb Wataghin University of Campinas (UNICAMP) Cidade Universitária Zeferino Vaz, arão Geraldo
Laboratory of Technological Plasmas Institute of Science and Technology São Paulo State University (UNESP), Av. Três de Março, 511
Department of Mechanical Engineering University of São Paulo (USP), Trabalhador São Carlense, 400
Department of Periodontology Dental Research Division Guarulhos University, Eng Prestes Maia, 88
Department of Dental Materials and Prosthodontics School of Dentistry at Araraquara São Paulo State University (UNESP), R. Humaitá, 1680
Laboratory of Technological Plasmas Institute of Science and Technology São Paulo State University (UNESP), Av. Três de Março, 511
FAPESP: 2018/04630-2
Fundo de Apoio ao Ensino, à Pesquisa e Extensão, Universidade Estadual de Campinas: 3164/18
