Autor(es): Guedes, Rodrigo C. M. ; Nogueira, Natália G. P. ; Fusco-Almeida, Ana M. [UNESP] ; Souza, Cláudia R. F. ; Oliveira, Wanderley P.
Data: 2022
Identificador Persistente: http://hdl.handle.net/11449/219532
Origem: Oasisbr
Assunto(s): Antimicrobial; Crude extracts; Petiveria alliacea
Made available in DSpace on 2022-04-28T18:56:08Z (GMT). No. of bitstreams: 0 Previous issue date: 2009-11-20
Petiveria alliacea L. (Phytolaccacea) is an herbaceous plant of great importance in traditional medicine. This species have been widely used in several applications such as antirheumatic, anticarcinogenic, anti-flu, antitussive, analgesic, insecticidal, acaricidal, as well as bactericide and fungicide. Currently, the pathogenic microorganisms are acquiring resistence against the traditional antibiotics, and the search for new herbal antimicrobial agents has been intensified. The objective of this study was to evaluate the antifungal and antibacterial activity of several leaf crude extracts of P. alliacea against several strains of bacterias and yeasts namely Bacilus subtilis, Pseudomonas aeruginosa, Escherichia coli, Streptococcus mutans, Staphylococcus aureus, Staphylococcus epidermidis, Enterococcus faecalis, Candida parapsilosis, Candida kefyr and Candida albicans, using microdilution method. Promising results were observed for the 70% v/v ethanolic extract which presented minimum inhibitory concentration (MIC) from 250 to 760 μg/mL for yeast. For the bacteria strains tested the MIC ranged between 240 to 3960 μg/mL, depending of the extractive solution tested.
Faculdade de Ciências Farmacêuticas Universidade de Ribeirão Preto, Ribeirão Preto - SP-14096-900
Faculdade de Ciências Farmacêuticas de Araraquara Universidade Estadual Paulista Júlio de Mesquita Filho UNESP, Araraquara - SP-14801-902
Faculdade de Ciências Farmacêuticas de Ribeirão Preto Universidade de São Paulo, Ribeirão Preto - SP-14040-903
Faculdade de Ciências Farmacêuticas de Araraquara Universidade Estadual Paulista Júlio de Mesquita Filho UNESP, Araraquara - SP-14801-902
