Role of cell death pathways in response to photodynamic therapy in gliomas

• Author(s): De Paula, Leonardo Barcelos ; Primo, Fernando Lucas [UNESP] ; Tedesco, Antonio Claudio
• Date: 2022
• Persistent ID: http://hdl.handle.net/11449/221140
• Origin: Oasisbr
• Document Type: Book part
• Language: English

Description

Made available in DSpace on 2022-04-28T19:10:59Z (GMT). No. of bitstreams: 0 Previous issue date: 2017-01-01

Deeper characterization of signaling pathways important in glioma growth is needed and may enable the development of new pharmacological agents, which could be utilized in new therapies for patients who do not respond to conventional antitumor therapies. Protein kinase B (PKB/Akt) and the transcription factor, nuclear factor kappa B (NF-kappaB), have garnered attention as potential targets for cell death induction and sensitization to chemotherapy in many tumor cell types such as lung cancer, ovarian cancer, and glioblastoma (Aggarwal, 2004; Kapoor et al., 2004; Sethi et al., 2007; Wu et al., 2008; Xu et al., 2009; Koul et al., 2010; Zanotto-Filho et al., 2010).

Department of Chemistry Center of Nanotechnology and Tissue Engineering Photobiology and Photomedicine Research Group Faculty of Philosophy Sciences and Letters of Ribeirão Preto University of São Paulo

Department of Bioprocess and Biotechnology São Paulo State University

Department of Bioprocess and Biotechnology São Paulo State University