Author(s): Lima Cardoso, Claudia Andrea [UNESP] ; Vilegas, Wagner [UNESP]
Date: 2022
Persistent ID: http://hdl.handle.net/11449/224127
Origin: Oasisbr
Subject(s): Apocynaceae; Droplet counter-current chromatography; Indole alkaloids; Tabernaemontana hilariana
Made available in DSpace on 2022-04-28T19:54:52Z (GMT). No. of bitstreams: 0 Previous issue date: 1999-01-01
This paper reports the separation of the indole alkaloids from the benzene extract of the root barks of Tabernaemontana hilariana (Apocynaceae). The crude alkaloid fraction was fractionated by droplet counter-current chromatography using a low polarity mixture (hexane:ethyl acetate:ethanol:water). Nine indole alkaloids (3-hydroxycoronaridine, coronaridine, voacangine, 3-(2-oxopropyl) coronaridine, voacangine hydroxyindolenine, ibogamine, voacangine pseudoindoxyl, coronaridine pseudoindoxyl and tabernanthine) were identified using thin layer chromatography, gas chromatography coupled with mass spectrometry and nuclear magnetic resonance spectroscopy.
Depto. de Química Organica Inst. de Quim. de Araraquara - Unesp, CP. 355, 14800-900 Araraquara-Sao Paulo
Depto. de Química Organica Inst. de Quim. de Araraquara - Unesp, CP. 355, 14800-900 Araraquara-Sao Paulo
