Author(s): Barbarini Ferraz, Lucieni Cristina [UNESP] ; Schellini, Silvana Artioli [UNESP] ; Wludarski, Sheila Lordelo ; Padovani, Carlos Roberto [UNESP] ; Müller, Sérgio [UNESP]
Date: 2022
Persistent ID: http://hdl.handle.net/11449/224915
Origin: Oasisbr
Subject(s): Adhesives/therapeutic use; Biomechanics; Cyanoacrylates; Histology; Oculomotor muscles/drug effects; Polyethylenes; Rabbits/surgery
Made available in DSpace on 2022-04-28T20:17:21Z (GMT). No. of bitstreams: 0 Previous issue date: 2007-03-01
Purpose: To evaluate fixation by a bioadhesive of the external ocular muscles to the porous polyethylene spheres. Methods: An experimental study was performed using eight white rabbits that underwent right eye enucleation with placement of 12 mm spheres of porous polyethylene. The rectus muscles (superior and inferior) were attached to the implant with a bioadhesive (2-octyl-cyanoacrylate) applied to the inferior side of the external muscles. Ninety days after surgery the orbital content was removed and 4 animals were submitted to a tensile strength test of the muscle-sphere attachment and the other 4 to histological evaluation. Results: The tensile strength test showed that the rupture force was similar between the muscle and porous polyethylene sphere bond attachment and normal external ocular muscles. The histologic evaluation showed fibrous tissue reaction and muscle-sphere attachment with no deleterious effects to the tissues; a capsule formation around the spheres and new vessels inside the implant were also observed. Conclusion: 2-octyl-cyanoacrylate provides strength adhesion between muscles and spheres, with surgery time reduction and does not provoke deleterious effects on the orbital tissues. Thus, the bioadhesive might be a good choice for use in the anophthalmic cavity reconstruction.
Depto. de Oftalmologia Otorrinolaringologia e Cirurgia de Cabeça e Pescoço Faculdade de Medicina Universidade Estadul Paulista Júlio Mesquita Filho, Botucatu, SP
Depto. de Oftalmologia Otorrinolaringologia e Cirurgia de Cabeça e Pescoço Faculdade de Medicina UNESP, Botucatu, SP 18618-970
Departamento de Bioestatística Instituto de Biociências UNESP, Botucatu, SP 18618-970
Departamento de Cirurgia Faculdade de Medicina UNESP, Botucatu, SP 18618-970
Depto. de Oftalmologia Otorrinolaringologia e Cirurgia de Cabeça e Pescoço Faculdade de Medicina Universidade Estadul Paulista Júlio Mesquita Filho, Botucatu, SP
Depto. de Oftalmologia Otorrinolaringologia e Cirurgia de Cabeça e Pescoço Faculdade de Medicina UNESP, Botucatu, SP 18618-970
Departamento de Bioestatística Instituto de Biociências UNESP, Botucatu, SP 18618-970
Departamento de Cirurgia Faculdade de Medicina UNESP, Botucatu, SP 18618-970
