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Clinicopathological analysis of oral mucous autoimmune disease: A 27-year study

Author(s): Arisawa, Emília Angela Loschiavo ; Almeida, Janete Dias [UNESP] ; Carvalho, Yasmin Rodarte [UNESP] ; Cabral, Luiz Antonio Guimarães [UNESP]

Date: 2022

Persistent ID: http://hdl.handle.net/11449/225090

Origin: Oasisbr

Subject(s): Autoimmune diseases; Erythema multiforme; Lichen planus; Mucous membrane; Pemphigoid; Pemphigus


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Made available in DSpace on 2022-04-28T20:39:01Z (GMT). No. of bitstreams: 0 Previous issue date: 2008-02-01

Objectives: The aim of the present study was to analyze the main clinical and histopathological features of autoimmune diseases with oral manifestations such as oral lichen planus (OLP); mucous membrane pemphigoid (MMP); pemphigus vulgaris (PV) and erythema multiforme (EM). Study design: Retrospective review of 5770 files from the Oral Pathology Laboratory of São José dos Campos Dental School, São Paulo State University (UNESP) comprising a 27-year period from 1974 to 2000. Results: The cases accounted for 64 (1.10%) of 5770 anatomopathological examinations performed over the study period. Among the autoimmune diseases diagnosed, 49 (76.56%) were OLP, 6 (9.37%) were MMP, 5 (7.82%) were EM and 4 (6.25%) were PV. Descriptive statistical analysis was used. Conclusion: The initial manifestations of most autoimmune diseases occur in the oral mucosa. An earlier diagnosis and proper therapeutic protocol will delay the dissemination of the lesions, thus greatly contributing to a better prognosis and quality of life of the patient. © Medicina Oral S. L.

Health Science Faculty Vale do Paraíba University - UNIVAP

Department of Biosciences and Oral Diagnosis São José Dos Campos Dental School São Paulo State University - UNESP

Department of Biosciences and Oral Diagnosis São José Dos Campos Dental School São Paulo State University - UNESP, São José Dos Campos, São Paulo

Department of Biosciences and Diagnosis São José Dos Campos Dental School São Paulo State University - UNESP

Department of Biosciences and Oral Diagnosis São José Dos Campos Dental School São Paulo State University - UNESP

Department of Biosciences and Oral Diagnosis São José Dos Campos Dental School São Paulo State University - UNESP, São José Dos Campos, São Paulo

Department of Biosciences and Diagnosis São José Dos Campos Dental School São Paulo State University - UNESP

Document Type Journal article
Language English
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