Author(s): Loschiavo Arisawa, Emilia Angela ; Almeida, Janete Dias [UNESP] ; Carvalho, Yasmin Rodarte [UNESP] ; Guimaraes Cabral, Luiz Antonio [UNESP]
Date: 2014
Persistent ID: http://hdl.handle.net/11449/22620
Origin: Oasisbr
Subject(s): autoimmune diseases; lichen planus; pemphigoid; mucous membrane; pemphigus; erythema multiforme
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Objectives: The aim of the present study was to analyze the main clinical and histopathological features of autoimmune diseases with oral manifestations such as oral lichen planus (OLP); mucous membrane pemphigoid (MMP); pemphigus vulgaris (PV) and erythema multiforme (EM). Study design: Retrospective review of 5770 files from the Oral Pathology Laboratory of Sao Jose dos Campos Dental School, São Paulo State University (UNESP) comprising a 27- year period from 1974 to 2000.Results: The cases accounted for 64 (1.10%) of 5770 anatomopathological examinations performed over the study period. Among the autoimmune diseases diagnosed, 49 (76.56%) were OLP, 6 (9.37%) were MMP, 5 (7.82%) were em and 4 (6.25%) were PV. Descriptive statistical analysis was used.Conclusion: The initial manifestations of most autoimmune diseases occur in the oral mucosa. An earlier diagnosis and proper therapeutic protocol will delay the dissemination of the lesions, thus greatly contributing to a better prognosis and quality of life of the patient.
São Paulo State Univ UNESP, Dept Biosci & Oral Diag, Sao Jose Campos Dent Sch, São Paulo, Brazil
Vale Paraiba Univ UNIVAP, Fac Hlth Sci, Sao Jose Dos Campos, Brazil
São Paulo State Univ UNESP, Dept Biosci & Oral Diag, Sao Jose Campos Dent Sch, São Paulo, Brazil
