Document details

Syphilis in pregnancy, factors associated with congenital syphilis and newborn conditions at birth

Author(s): de Almeida, Anelisa Soares [UNESP] ; Andrade, Juliane ; Fermiano, Rosemary [UNESP] ; Jamas, Milena Temer [UNESP] ; Carvalhaes, Maria Antonieta de Barros Leite [UNESP] ; Parada, Cristina Maria Garcia de Lima [UNESP]

Date: 2022

Persistent ID: http://hdl.handle.net/11449/229507

Origin: Oasisbr

Subject(s): Congenital syphilis; Longitudinal studies; Pregnancy; Risk factors; Syphilis


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Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Objectives: to investigate factors associated with the occurrence of congenital syphilis in pregnant women with syphilis and to describe the cases of this disease regarding the justification for notification and aspects related to the newborn. Method: cohort study, with data collection between July and September 2017 which included 158 pregnant women diagnosed with syphilis during pregnancy, reported between 2013 and 2015. The characteristics of pregnant women and newborns are presented descriptively. The outcome under study was the occurrence or not of congenital syphilis. Sociodemographic exposure variables related to prenatal care and the adequacy of maternal syphilis treatment were analyzed by the stepwise selection criteria, and those that presented p<0.20, included in adjusted analysis, when critical p <0.05 was adopted. Results: most pregnant women with syphilis were white, had nine or more years of schooling and did not work. Among the participants, 74 (46.8%) had a newborn with congenital syphilis. Independently, the number of prenatal consultations was the only factor associated with congenital syphilis: as the number of consultations increased, the occurrence decreased (p=0.013, OR=0.87, 95%CI=0.79-0.97). The non-treatment of the mother and partner were the most frequent justifications for defining the case of congenital syphilis, and 33 newborns with syphilis presented complications at birth. Conclusion: considering the association with the number of prenatal consultations, in order to reduce cases of congenital syphilis, the municipality should modify the follow-up in this period, offering consultations, developing health education actions, implementing diagnostic investigation and appropriate treatment for pregnant women, and partnership when necessary.

Universidade Estadual Paulista Júlio de Mesquita Filho Faculdade de Medicina de Botucatu Departamento de Enfermagem. Botucatu

Universidade de Brasília Faculdade de Ciências da Saúde Departamento de Enfermagem, Distrito Federal

Universidade Estadual Paulista Júlio de Mesquita Filho Faculdade de Medicina de Botucatu Departamento de Enfermagem. Botucatu

CAPES: 27/2016

Document Type Journal article
Language English
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