Autor(es): da Silva, Letícia Fernanda ; Nobre, Caio Rodrigues [UNESP] ; Moreno, Beatriz Barbosa ; Pereira, Camilo Dias Seabra ; de Souza Abessa, Denis Moledo [UNESP] ; Choueri, Rodrigo Brasil ; Gusso-Choueri, Paloma Kachel [UNESP] ; Cesar, Augusto
Data: 2022
Identificador Persistente: http://hdl.handle.net/11449/230618
Origem: Oasisbr
Assunto(s): 17α-Ethynylestradiol; Ecotoxicology; Microplastics; Transport; Triclosan; Ucides cordatus
Made available in DSpace on 2022-04-29T08:41:15Z (GMT). No. of bitstreams: 0 Previous issue date: 2022-04-01
Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
Methods to assess the effects of contaminants on marine organisms typically involve euthanasia to obtain samples, but less invasive techniques may be more appropriate for working with threatened species. In this study, were assessed the biological responses of crabs exposed to microplastics and contaminants of emerging concern. Biochemical and cellular effects (lipid peroxidation, DNA damage, cholinesterase activity, and lysosomal membrane stability) in hemolymph were analyzed in a kinetic study, at 3 and 7 days, in U. cordatus exposed to microplastics spiked with Triclosan (TCS) or 17α-Ethynylestradiol (EE2). The results showed that the contaminants were produced toxic effects in the crabs exposed either to the microplastics alone (oxidative stress, genotoxicity, and neurotoxicity), or to microplastics with TCS or EE2 adsorbed (neurotoxic and cytotoxic). The present study showed the responsiveness of non-lethal analyzes to understanding the biological effects of combined exposure to microplastics and chemical pollution.
Department of Ocean Sciences Sea Institute Federal University of São Paulo (CBS-Unifesp), Rua Carvalho de Mendonça, 144, Santos
Biosciences Institute São Paulo State University (CLP-Unesp), Praça Infante Dom Henrique, s/n, Parque Bitaru, São Vicente
Ecotoxicology Laboratory Santa Cecília University (Unisanta), Rua Oswaldo Cruz, 266, Santos
Biosciences Institute São Paulo State University (CLP-Unesp), Praça Infante Dom Henrique, s/n, Parque Bitaru, São Vicente
