Author(s): Santiago, Karina Basso ; Piana, Gilce Maria ; Conti, Bruno José ; Cardoso, Eliza de Oliveira ; Andrade, Bruna Fernanda Murbach Teles ; Zanutto, Mirella Rossitto ; Rall, Vera Lúcia Mores ; Fernandes, Ary ; Sforcin, José Maurício
Date: 2022
Persistent ID: http://hdl.handle.net/11449/231402
Origin: Oasisbr
Subject(s): Antibacterial action; Chlorhexidine; Odontological product; Propolis
Made available in DSpace on 2022-04-29T08:45:16Z (GMT). No. of bitstreams: 0 Previous issue date: 2018-06-23
Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
Propolis is a bee product with several biological properties. This study aimed at investigating a propolis-containing mouthwash, its organoleptic properties, microbial contamination and its antibacterial action in vitro. This mouthwash was assessed in vivo to control dental plaque in humans. The presence of microorganisms was analyzed and the minimum inhibitory concentration against Streptococcus mutans was determined. A comparative study was done in vivo using propolis, chlorhexidine, and propolis plus chlorhexidine in lower concentrations for 14 days. Dental plaque was analyzed by the Patient Hygiene Performance (PHP) index. The odontological product was yellow, cloudy, free of microbial contamination, and exerted an inhibitory action in vitro. Individuals who used a propolis-containing mouthwash for 14 consecutive days in combination or not to chlorhexidine showed a similar PHP index to chlorhexidine alone. The product exerted an antibacterial action in vitro and in vivo, exhibiting a positive action in the control of dental plaque.
Department of Microbiology and Immunology Institute of Biosciences of Botucatu
FAPESP: 2011/22112-0
FAPESP: 2012/14614-8
