Author(s): Guerreiro, Gisleine ; Lima, Janete Eliza S. de ; Fernandes, João Batista ; Silva, M. Fátima das G. F. da ; Vieira, Paulo Cezar ; Magalhães, Claudia Maria I. [UNESP] ; Pagnocca, Fernando Carlos [UNESP] ; Bueno, Odair Corrêa [UNESP] ; Hebling, Maria José Aparecida [UNESP] ; Pirani, José Rubens
Date: 2014
Persistent ID: http://hdl.handle.net/11449/756
Origin: Oasisbr
Subject(s): Pilocarpus riedelianus; sesquiterpenes; antimicrobial activity
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Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
Pilocarpus riedelianus was studied in order to obtain compounds with activity against fungi and bacteria. The dichloromethane extract, the most active one, was chromatographed yielding hexane and dichloromethane fractions. Six known sesquiterpenes, alpha-calacorene, beta-calacorene, gamma-calacorene, cadalene, sesquichamaenol and 1-hydroxy-1,3,5-bisabolatrien-10-one were identified in the hexane fractions. The identification of these compound was done by NMR and GC/MS analyses. The hexane fraction from the dichloromethane extract showed activity against several fungi and bacteria.
Universidade Federal de São Carlos (UFSCar) Departamento de Química
Universidade Estadual Paulista Instituto de Biociências Centro de Estudos de Insetos Sociais
Universidade de São Paulo Instituto de Biociências Departamento de Botânica
Universidade Estadual Paulista Instituto de Biociências Centro de Estudos de Insetos Sociais
