Autor(es):
Roman-Torres, Caio Vinícius Gonçalves ; Aquino, Davi Romeiro ; Cortelli, Sheila Cavalca ; Franco, Gilson Cesar Nobre ; Santos, Juliana Guimaraes dos ; Corraini, Priscila ; Holzhausen, Marinella ; Diniz, Marina Goncalves ; Gomez, Ricardo Santiago ; Cortelli, José Roberto
Data: 2019
Origem: Oasisbr
Assunto(s): Actinobacillus Actinomycetemcomitans; Periodontitis; Serotype; Prevalence; Localized Juvenile Periodontitis; Actinobacillus-Actinomycetemcomitans; Subgingival Plaque; Porphyromonas-Gingivalis; Adult Periodontitis; Different Strains; Leukotoxin Gene; Disease; Chinese; Association; Dentistry, Oral Surgery & Medicine; Dentistry, Oral Surgery & Medicine
Descrição
Made available in DSpace on 2019-09-12T16:53:32Z (GMT). No. of bitstreams: 0 Previous issue date: 2010
Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
Objective: Previous studies have suggested that Aggregatibacter actinomycetemcomitans is involved in the aetiology of aggressive periodontitis as well as chronic periodontitis. In addition, some authors have also reported that serotype-specific antigens of A. actinomycetemcomitans determine the severity of disease. This study aimed to elucidate the prevalence of A. actinomycetemcomitans and the distribution of A. actinomycetemcomitans serotypes in Brazilian subjects with chronic periodontitis. Design: A total of 486 individuals were enrolled in this survey. All patients received clinical examinations that included periodontal pocket depth, clinical attachment loss, plaque, and gingival indexes. Subgingival samples were taken for microbial analysis. The genomic DNA of A. actinomycetemcomitans was provided by PCR. Results: Out of 486 subjects examined, A. actinomycetemcomitans was isolated in 85 (17.5%) individuals. Out of 85 positive samples, 68 were infected by at least 1 serotype, 7 by mixed infection, and 10 were non-serotyped. Serotypes d and f were not detected. Serotype c showed the highest prevalence (52.9%), followed by serotype a (31.8%). Conclusions: Intragroup analysis revealed that, in slight/moderate periodontitis, serotypes c and a were significantly more prevalent than serotypes b and d-f; the prevalence of serotype c in severe periodontitis was significantly greater than that of serotypes a and b. Our data were similar in Asian and Eurasian populations. (C) 2010 Elsevier Ltd. All rights reserved.
[Goncalves Roman-Torres, Caio Vinicius; Aquino, Davi Romeiro; Cortelli, Sheila Cavalca; Nobre Franco, Gilson Cesar; dos Santos, Juliana Guimaraes; Holzhausen, Marinella; Cortelli, Jose Roberto] Universidade de Taubaté (Unitau), Dept Periodontol & Prevent Dent, Dent Res Div, BR-12020330 Taubate, SP, Brazil
[Corraini, Priscila] Univ Sao Paulo, Div Periodont, Dept Stomatol, Sch Dent, BR-05508900 Sao Paulo, Brazil
[Diniz, Marina Goncalves; Gomez, Ricardo Santiago] Univ Fed Minas Gerais, Dept Mol Biol, Sch Dent, BR-31270901 Belo Horizonte, MG, Brazil
