Document details

Hair cortisol concentrations are associated with dental anxiety during pregnancy

Author(s): Viitaniemi, Hilja ; Suominen, Auli ; Karlsson, Linnea ; Mustonen, Paula ; Kortesluoma, Susanna ; Rantavuori, Kari ; Rodrigues, Ana João ; Coimbra, Bárbara Guimarães Salazar ; Karlsson, Hasse ; Lahti, Satu

Date: 2021

Persistent ID: http://hdl.handle.net/1822/73483

Origin: RepositóriUM - Universidade do Minho

Subject(s): Dental anxiety; Hair cortisol; Depression; General anxiety; FinnBrain; Science & Technology


Description

Dental anxiety (DA) and hair cortisol concentrations (HCC) are associated with psychological symptoms and vary during pregnancy. We aimed to examine the association between HCC and DA at two points of pregnancy. Participants were pregnant mothers (n = 533) drawn from the FinnBrain Birth Cohort Study donating a hair sample at gestational week (gwk) 24 (n = 442) and/or at delivery (n = 176) and completed questionnaires on DA. Two groups, HCC1 and HCC2, treated as separate in the analyses, were formed according to the hair sample donation time i.e., gwk24 and delivery. 85 subjects were included in both groups. MDAS, EPDS, and SCL-90 were used to measure DA, depressive and anxiety symptoms, respectively, at gwk14 for the HCC1 group and gwk34 for the HCC2 group. The association between DA and HCC was studied with a binary logistic regression model, adjusted for anxiety and depressive symptoms, age, BMI, and smoking status. Individuals with high DA had lower HCC levels at gwk24 (OR = 0.548; 95% CI = 0.35–0.86; p = 0.009), but the association was not statistically significant at the delivery (OR = 0.611; 95% CI = 0.28–1.33; p = 0.216). The independent association between HCC and DA in pregnant women suggests that long-term cortisol levels could play a role in the endogenous etiology of DA. Further studies are however, needed.

This research was funded by the Academy of Finland (grant #134950 to HK and grant #308176 to LK), Jane and Aatos Erkko Foundation, Signe and Ane Gyllenberg Foundation, and State Research Grants. AJR is funded by FCT under the project PTDC/MED-NEU/29071/2017.

Document Type Journal article
Language English
Contributor(s) Universidade do Minho
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