Document details

Tartrate-resistant acid phosphate as biomarker of bone turnover over the lifespan and different physiologic stages in sheep

Author(s): Camassa, José A. ; Diogo, Camila C. ; Bordelo, João P. A. ; Bonelli, Marília de A. ; Viegas, Carlos A. ; Azevedo, Jorge T. ; Dourado, Nuno ; Dias, Isabel R.

Date: 2017

Persistent ID: https://hdl.handle.net/1822/52127

Origin: RepositóriUM - Universidade do Minho

Subject(s): ALP; Bone tissue; Serum minerals; Sheep; Tartrate-resistant acid phosphatase


Description

Currently, the best resources for assessment of bone tissue using imaging techniques are expensive and available in few medical facilities, thus serum or urinary bone turnover biomarkers could be useful as early indicators of prognosis. However, there is a wide range of variability in bone turnover markers due to several factors, such as different ages and metabolic stages, thus it is important to have as much data published on the subject as possible. The aim of this study was therefore to generate a reference range for alkaline phosphatase (ALP) and tartrate-resistant acid phosphatase (TRAP) and validate the already published data.

Document Type Journal article
Language English
Contributor(s) Universidade do Minho
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