Magnetic/plasmonic liposomes as nanocarriers for novel antitumor tricyclic lactones against non-small cell lung cancer

• Autor(es): Rodrigues, Ana Rita Oliveira ; Rio, Irina Soraia Rainho ; Rodrigues, J. M. ; Queiroz, Maria João R. P. ; Calhelha, Ricardo C. ; Ferreira, Isabel C. F. R. ; Almeida, B. G. ; Pires, Ana ; Pereira, A. M. ; Araújo, J. P. ; Coutinho, Paulo J. G. ; Castanheira, Elisabete M. S.
• Data: 2020
• Identificador Persistente: https://hdl.handle.net/1822/66159
• Origem: RepositóriUM - Universidade do Minho
• Assunto(s): Magnetic nanoparticles; Magnetoliposomes; Magnetic/plasmonic nanostructures; Dual cancer therapy
• Tipo de Documento: Outro
• Idioma: Inglês
• Contribuidor(es): Universidade do Minho

Descrição

In this work, MnFe2O4/Au core/shell nanoparticles (NPs) and MnFe2O4 NPs decorated with Au NPs were synthesized and the structural, spectroscopic and magnetic properties evaluated. The prepared NPs were covered with a lipid bilayer, forming solid magnetoliposomes (SMLs). The heating capabilities of the nanosystems were assessed through the fluorescence quenching of Nile Red (incorporated in the lipid bilayer of the SMLs) under irradiation.