Author(s): Ramos, Adauto Versiani ; Silva, Ivani Novato ; Goulart, Eugênio Marcos Andrade
Date: 2008
Origin: Oasisbr
Subject(s): Growth; Growth velocity; Adult height; Growth hormone; Turner syndrome
Document details
Turner syndrome: searching for better outcomes
Description
OBJECTIVES: To assess the results of growth hormone on the growth of girls with Turner Syndrome and identify relevant parameters to improve outcomes. METHODS: Growth velocity and final height were studied in a historical cohort of 41 girls, regularly followed up for hormone distribution at three referral centers. The influence of oxandrolone and of estrogens on the final height was analyzed. The girls (initial chronological age=8.9±3.4years; initial bone age=7.0±3.1years) used 0.19 mg/kg/week of growth hormone for 4.0 ± 2.0 years. RESULTS: In the first year, growth velocity increased by 71.5% in 41 girls and 103.4% in those who reached final height (11 girls). The whole group had a gain in the height SDS of 0.8 ± 0.7 (p
Document Type
Journal article
Language English
Language English
