The influence of aerobic fitness status on ventilatory efficiency in patients with coronary artery disease

• Author(s): Prado, Danilo M.L. ; Rocco, Enéas A. ; Silva, Alexandre G. ; Silva, Priscila F. ; Lazzari, Jaqueline M. ; Assumpção, Gabriela L. ; Thies, Sheyla B. ; Suzaki, Claudia Y. ; Puig, Raphael S. ; Furlan, Valter
• Date: 2015
• Origin: Oasisbr
• Document Type: Journal article
• Language: English

Description

OBJECTIVE: To test the hypotheses that 1) coronary artery disease patients with lower aerobic fitness exhibit a lower ventilatory efficiency and 2) coronary artery disease patients with lower initial aerobic fitness exhibit greater improvements in ventilatory efficiency with aerobic exercise training. METHOD: A total of 123 patients (61.0±0.7 years) with coronary artery disease were divided according to aerobic fitness status into 3 groups: group 1 (n = 34, peak VO2;17.5 and ;24.5 ml/kg/min). All patients performed a cardiorespiratory exercise test on a treadmill. Ventilatory efficiency was determined by the lowest VE/VCO2 ratio observed. The exercise training program comprised moderate-intensity aerobic exercise performed 3 times per week for 3 months. Clinicaltrials.gov: NCT02106533 RESULTS: Before intervention, group 1 exhibited both lower peak VO2 and lower ventilatory efficiency compared with the other 2 groups (p