Document details

Biocompatible Bacterial Cellulose-Poly(2-hydroxyethyl methacrylate) Nanocomposite Films

Author(s): Figueiredo, Andrea G. P. R. ; Figueiredo, Ana R. P. ; Alonso-Varona, Ana ; Fernandes, Susana C. M. ; Palomares, Teodoro ; Rubio-Azpeitia, Eva ; Barros-Timmons, Ana ; Silvestre, Armando J. D. ; Neto, Carlos Pascoal ; Freire, Carmen S. R.

Date: 2013

Persistent ID: http://hdl.handle.net/10773/19769

Origin: RIA - Repositório Institucional da Universidade de Aveiro

Subject(s): CELLULOSE; HYDROGELS; COMPOSITES; SCAFFOLDS; DIFFUSION; DELIVERY; PHEMA


Description

A series of bacterial cellulose-poly(2-hydroxyethyl methacrylate) nanocomposite films was prepared by in situ radical polymerization of 2-hydroxyethyl methacrylate (HEMA), using variable amounts of poly(ethylene glycol) diacrylate (PEGDA) as crosslinker. Thin films were obtained, and their physical, chemical, thermal, and mechanical properties were evaluated. The films showed improved translucency compared to BC and enhanced thermal stability and mechanical performance when compared to poly(2-hydroxyethyl methacrylate) (PHEMA). Finally, BC/PHEMA nanocomposites proved to be nontoxic to human adipose-derived mesenchymal stem cells (ADSCs) and thus are pointed as potential dry dressings for biomedical applications.

Document Type Journal article
Language English
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