Autor(es): Montz, R ; Perez-Castejón, MJ ; Jurado, JA ; Martín-Comín, J ; Esplugues, E ; Salgado, L ; Ventosa, A ; Cantinho, G ; Sá, EP ; Fonseca, AT ; Pedroso de Lima, J
Data: 1996
Identificador Persistente: http://hdl.handle.net/10400.4/512
Origem: Repositório do Centro Hospitalar e Universitário de Coimbra
Assunto(s): Angiografia Coronária; Tomografia de Emissão de Fotão Único; Compostos Organofosforados
Technetium-99m tetrofosmin (Myoview) has unique properties for myocardial perfusion imaging very early after injection of the tracer. We used a very short same-day rest/stress protocol, to be performed within 2 h and evaluated its diagnostic accuracy. The study included 144 patients from seven Spanish and four Portuguese centres with a diagnosis of uncomplicated coronary artery disease (CAD); 78 patients (54%) had no history of prior myocardial infarction. Patients were injected with /=50%) was achieved with a sensitivity of 64% for the left anterior descending artery, 49% for the left circumflex artery and 86% for the right coronary artery, and an accuracy of 71%, 72% and 73% respectively. Concordance of SPET and CA was 62% for single-vessel disease and 68% for multivessel disease. In conclusion, this Spanish-Portuguese multicentre clinical trial confirmed, in a considerable number of patients who underwent coronary angiography, the feasibility of 99mTc tetrofosmin (Myoview) rest/stress myocardial SPET using a very short protocol (2 h).
