Author(s): Mohanlal, Urmik ; Salgado, Duarte
Date: 2021
Persistent ID: http://hdl.handle.net/10362/126489
Origin: Repositório Institucional da UNL
Subject(s): Antineoplastic agents/ therapeutic use; Cranial irradiation; Lung neoplasms; Meningeal carcinomatosis; Clinical Neurology; Cellular and Molecular Neuroscience; SDG 3 - Good Health and Well-being
Publisher Copyright: © Author(s) (or their employer(s)) and Sinapse 2021.
Leptomeningeal carcinomatosis is a rare complication of several types of cancer. There are many possible clinical features, and the diagnosis is made with brain imaging and cytological analysis of cerebrospinal fluid. Treatment is widely debated and, concerning overall survival, there does not seem to exist a treatment option which is definitely superior. The present work describes the case of a 53-year-old man diagnosed with leptomeningeal carcinomatosis secondary to lung adenocarcinoma, who was treated with whole brain radiation therapy and, upon relapse, with intrathecal chemotherapy, showing both an above-average overall survival and a high performance status.
