Author(s):
Simão, Ana Y. ; Antunes, Mónica ; Cabral, Emanuel ; Oliveira, Patrik ; Rosendo, Luana M. ; Brinca, Ana Teresa ; Alves, Estefânia ; Marques, Hernâni ; Rosado, Tiago ; Passarinha, Luís A. ; Andraus, Maristela ; Barroso, Mário ; Gallardo, Eugenia
Date: 2022
Persistent ID: http://hdl.handle.net/10362/143809
Origin: Repositório Institucional da UNL
Project/scholarship:
info:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/UIDB%2F00709%2F2020/PT;
info:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/UIDP%2F00709%2F2020/PT;
info:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/UIDB%2F04378%2F2020/PT;
info:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/UIDP%2F04378%2F2020/PT;
info:eu-repo/grantAgreement/FCT/POR_CENTRO/2020.09070.BD/PT;
Subject(s): health problems; new psychoactive substances; toxicity; Pollution; Public Health, Environmental and Occupational Health; Health, Toxicology and Mutagenesis; SDG 3 - Good Health and Well-being
Description
Funding: The Associate Laboratory Institute for Health and Bioeconomy–i4HB (project LA/P/0140/2020) which are financed by National Funds from FCT/MCTES. Ana Y. Simão and Mónica Antunes acknowledge the PhD fellowships from FCT (2020.05765.BD). Publisher Copyright: © 2022 by the authors. Licensee MDPI, Basel, Switzerland.
The emergence of new psychoactive substances has earned a great deal of attention, and several reports of acute poisoning and deaths have been issued involving, for instance, synthetic opiates. In recent years, there have been profound alterations in the legislation concerning consump-tion, marketing, and synthesis of these compounds; rapid alert systems have also been subject to changes, and new substances and new markets, mainly through the internet, have appeared. Their effects and how they originate in consumers are still mostly unknown, primarily in what concerns chronic toxicity. This review intends to provide a detailed description of these substances from the point of view of consumption, toxicokinetics, and health consequences, including case reports on intoxications in order to help researchers and public health agents working daily in this area.
