Author(s): Moura, Pedro Catalão ; Raposo, Maria ; Vassilenko, Valentina
Date: 2024
Persistent ID: http://hdl.handle.net/10362/172332
Origin: Repositório Institucional da UNL
Subject(s): Biomarkers; Breath Sampling; Exhaled Breath; Non-Carcinogenic Diseases; VOCs; Volatile Organic Compounds; Biochemistry; Clinical Biochemistry; Biochemistry, medical; SDG 3 - Good Health and Well-being
Funding Information: This work was financed by Fundação para a Ciência e Tecnologia (FCT – Portugal) through the grants UIDB/04559/2020(LIBPhys), and UIDP/04559/2020(LIBPhys) and PD/BDE/150627/2020. Funding Information: The authors would like to thank Fundação para a Ciência e Tecnologia (FCT - Portugal) for financing the grants UIDB/04559/2020(LIBPhys) and UIDP/04559/2020(LIBPhys). PCM would like to thank Fundação para a Ciência e Tecnologia (FCT - Portugal) for financing the grant PD/BDE/150627/2020 from the Doctoral NOVA I4H Program. Publisher Copyright: © 2023 The Author(s)
The analysis of volatile organic compounds (VOCs) from human matrices like breath, perspiration, and urine has received increasing attention from academic and medical researchers worldwide. These biological-borne VOCs molecules have characteristics that can be directly related to physiologic and pathophysiologic metabolic processes. In this work, gathers a total of 292 analytes that have been identified as potential biomarkers for the diagnosis of various non-carcinogenic diseases. Herein we review the advances in VOCs with a focus on breath biomarkers and their potential role as minimally invasive tools to improve diagnosis prognosis and therapeutic monitoring.
