Document details

Long-term exposure to ambient air pollution and its association with mental wellbeing, depression and anxiety

Author(s): Pinheiro-Guedes, Lara ; Sousa-Uva, Mafalda ; Gusmão, Ricardo ; Martinho, Clarisse ; Matias Dias, Carlos ; da Conceição, Virgínia ; Gomes Quelhas, Carlos ; Saldanha Resendes, Daniel ; Gaio, Vânia

Date: 2024

Persistent ID: http://hdl.handle.net/10362/172777

Origin: Repositório Institucional da UNL

Subject(s): Air Pollution/adverse effects; Anxiety Disorders; Depressive Disorders; Environmental Exposure; Mental Health; Particulate Matter/adverse effects; Stress, Psychological; Medicine(all); SDG 3 - Good Health and Well-being


Description

Funding Information: The Portuguese National Health Examination Survey was developed as part of a project financed under the Public Health Initiatives Programme (\u201CImprovement of epidemiological health information to support public health decision and management in Portugal. Towards reduced inequalities, improved health and bilateral cooperation\u201D) with a \u20AC1 500 000 grant from Iceland, Liechtenstein and Norway, the EEA Grants and the Portuguese Government. This research did not receive any specific grant from funding agencies in the public, commercial, or not-for-profit sectors. Publisher Copyright: Copyright © Ordem dos Médicos 2024.

Introduction: Exposure to ambient air pollution may play a role in the onset of common mental disorders like depressive and anxiety disorders. The association of long-term exposure to particles smaller than 10 μm (PM10) with these diseases remains unclear. This study aimed to estimate the association of long-term exposure to PM10 with mental well-being and the frequency of probable diagnosis of common mental disorders. Methods: A nationally representative cross-sectional study was done in mainland Portugal. Long-term exposure was estimated through one-year average concentrations of PM10, calculated with data from the Portuguese Environment Agency, attributed individually considering individuals’ postal codes of residence. The mental well-being and the probable diagnosis of common mental disorders were ascertained through the five-item Mental Health Inventory scale. Linear and Robust Poisson regression models were computed to estimate change percentages, prevalence ratios (PR), and their 95% confidence intervals (95% CI). Results: The median (interquartile range) concentration of PM10 was 18.6 (15.3 - 19.3) μg/m3. The mental well-being score was 72 (56 - 84) points, on a scale from 0 to 100. A probable diagnosis of common mental disorders was found in 22.7% (95% CI: 20.0 to 25.6). Long-term exposure to PM10 was associated with a non-statistically significant decrease in the mental well-being score [for each 10 μg/m3 increment in one-year average PM10 concentrations, there was a 2% (95% CI: -8 to 4) decrease], and with a non-statistically significant increase in the common mental health frequency (PR = 1.012, 95% CI: 0.979 to 1.045). Conclusion: We did not find statistically significant associations between long-term exposure to PM10 and mental well-being or the frequency of probable diagnosis of common mental disorders. These results may be explained by the reduced variability in the exposure values, given the geographical distribution and functioning of the network of air quality monitoring stations. This study contributes with evidence for low levels of air pollutants, being one of the first to adjust for individual and aggregate-level variables. Moreover, to the best of our knowledge, this was the first nationally representative, population-based study conducted on the Portuguese population using real-life data. Maintaining a robust and nationwide air quality monitoring network is essential for obtaining quality exposure data.

Document Type Journal article
Language Multiple languages
Contributor(s) Comprehensive Health Research Centre (CHRC) - Pólo ENSP; Centro de Investigação em Saúde Pública (CISP/PHRC); Escola Nacional de Saúde Pública (ENSP); RUN
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