Autor(es): Paiva, Raphaella ; Ferreira, Clarissa Pellegrini ; Lima, Daína ; Mattos, Jacó Joaquim ; Pessatti, Tomás Bohn ; Tisca, Juliana Fabrício ; Saldaña-Serrano, Miguel ; Nogueira, Diego José ; Bebianno, Maria ; Bainy, Afonso Celso Dias
Data: 2024
Identificador Persistente: http://hdl.handle.net/10400.1/25976
Origem: Sapientia - Universidade do Algarve
Assunto(s): Crassostrea gigas; Bivalve; Antioxidant defense; Emergent contaminant; Mariculture
The activities of catalase (CAT), glutathione peroxidase (GPx), glutathione reductase (GR), glucose-6-phosphate dehydrogenase (G6PDH), and glutathione-S-transferase (GST) were evaluated in the gills (GI) and digestive gland (DG) of Magallana gigas oysters exposed to tamoxifen (TAM) at environmental concentrations of 10 and 100 ng L- 1 for 1 and 4 days. A higher CAT activity in the GI and DG and higher GPx activity only in the DG was observed of oysters exposed to both concentrations after 1 day. Furthermore, a significant increase in GR and G6PDH, was detected in the DG after 1 day of exposure to 10 ng L- 1 and only G6PDH activity increase after 1 day of exposure to 10 ng L- 1 in the GI. This suggests that the DG is a tissue more sensitive to TAM exposure and was confirmed with the individual Integrated Biomarker Response version 2 index (IBRv2i), highlighting the acute stress caused by TAM and a cellular adaptation.
