Determinants of HIV-1 transmission clusters and transmitted drug resistance in men who have sex with men: a multicenter study in Portugal (2014-2019)

• Author(s): Abrantes, Ricardo ; Pimentel, Victor ; Sebastião, Cruz ; Miranda, Mafalda N. S. ; Seabra, Sofia ; Silva, Ana Rita ; Diniz, António ; Ascenção, Bianca ; Piñeiro, Carmela ; Koch, Carmo ; Rodrigues, Catarina ; Caldas, Cátia ; Morais, Célia ; Faria, Domitília ; Silva, Elisabete Gomes da ; Teófilo, Eugénio ; Monteiro, Fátima ; Roxo, Fausto ; Maltez, Fernando ; Rodrigues, Fernando ; Gaião, Guilhermina ; Ramos, Helena ; Costa, Inês ; Diogo, Isabel ; Germano, Isabel ; Simões, Joana ; Oliveira, Joaquim ; Ferreira, José ; Poças, José ; Cunha, José Saraiva da ; Soares, Jorge ; Mansinho, Kamal ; Pedro, Liliana ; Aleixo, Maria João ; Gonçalves, Maria João ; Manata, Maria José ; Mouro, Margarida ; Serrado, Margarida ; Caixeiro, Micaela ; Marques, Nuno ; Costa, Olga ; Pacheco, Patrícia ; Proença, Paula ; Rodrigues, Paulo ; Pinho, Raquel ; Tavares, Raquel ; Abreu, Ricardo Correia de ; Real, Rita Côrte ; Serrão, Rosário ; Castro, Rui Sarmento e ; Nunes, Sofia ; Faria, Telo ; Baptista, Teresa ; Simões, Daniel ; Mendão, Luis ; Martins, M. Rosário O. ; Gomes, Perpétua ; Pingarilho, Marta ; Abecasis, Ana B.
• Date: 2025
• Persistent ID: http://hdl.handle.net/10400.1/27156
• Origin: Sapientia - Universidade do Algarve
• Subject(s): HIV-1; Men who have sex with men; Portugal; Transmission cluster; Drug resistance
• Document Type: Journal article
• Language: English
• Contributor(s): Sapientia

Description

In the EU/EEA, men who have sex with men (MSM) is a priority group for the prevention and control of HIV-1 infection. In Portugal, the 2023 HIV incidence rate was 8.2 per 100,000 inhabitants, with 876 new infections, 41.7% in MSM. We aim to characterize HIV-1 transmission clusters (TC) and transmitted drug resistance (TDR) and its sociodemographic, behavioral, clinical, and viral genomic determinants in MSM newly diagnosed in Portugal between 2014 and 2019.