Author(s): Lana-Peixoto,Marco Aurélio ; Campos,Wesley Ribeiro ; Reis,Pedro Augusto Costa ; Campos,Christian Marcellus Camargo ; Rodrigues,Carlos Alberto
Date: 2014
Origin: Oasisbr
Subject(s): Tonic pupil; Mydriasis; Leprosy; Iritis; Iris/injuries; Atrophy; Case reports
Pupil abnormalities in leprosy usually result from chronic iritis with loss of stroma, iris miosis, a sluggish reaction to light, and poor dilation in response to anticholinergic mydriatics. We report two patients with long-standing lepromatous leprosy who developed tonic pupils characterized by mydriasis, absence of reaction to light and hypersensitivity to weak cholinergic solution. Examination revealed iritis and iris atrophy. In both cases, instillation of dilute 0.1% pilocarpine caused miosis in the affected eyes. Tonic pupil occurs in many conditions, but its association with leprosy had not been previously reported.
