Author(s):
Gondim,Francisco de Assis Aquino ; Barreira,Amilton Antunes ; Claudino,Rinaldo ; Cruz,Márcia Waddington ; Cunha,Francisco Marcos Bezerra da ; Freitas,Marcos Raimundo Gomes de ; França Jr,Marcondes Cavalcante ; Gonçalves,Marcus Vinícius Magno ; Marques Jr,Wilson ; Nascimento,Osvaldo José Moreira ; Oliveira,Acary Souza Bulle ; Pereira,Raquel Campos ; Pupe,Camila ; Rotta,Francisco Tellechea ; Schestatsky,Pedro
Date: 2018
Origin: Oasisbr
Subject(s): small fiber neuropathy; unmyelinated nerve fibers
Description
ABSTRACT The aim of this study was to describe the results of a Brazilian Consensus on Small Fiber Neuropathy (SFN). Fifteen neurologists (members of the Brazilian Academy of Neurology) reviewed a preliminary draft. Eleven panelists got together in the city of Fortaleza to discuss and finish the text for the manuscript submission. Small fiber neuropathy can be defined as a subtype of neuropathy characterized by selective involvement of unmyelinated or thinly myelinated sensory fibers. Its clinical picture includes both negative and positive manifestations: sensory (pain/dysesthesias/pruritus) or combined sensory and autonomic complaints, associated with an almost entirely normal neurological examination. Standard electromyography is normal. A growing list of medical conditions is associated with SFN. The classification of SFN may also serve as a useful terminology to uncover minor discrepancies in the normal values from different neurophysiology laboratories. Several techniques may disclose sensory and/or autonomic impairment. Further studies are necessary to refine these techniques and develop specific therapies.
