Vogt-Koyanagi-Harada syndrome: a discussion about resistance to corticotherapy

• Autor(es): Dias,Natália de Carvalho ; Ventura,Camila V.
• Data: 2021
• Origem: Oasisbr
• Assunto(s): Vogt-Koyanagi-Harada syndrome; Uveitis; Retinal detachment; Steroids; Pulse therapy, drug
• Tipo de Documento: Relatório
• Idioma: Inglês

Descrição

ABSTRACT Vogt-Koyanagi-Harada (VKH) syndrome is an inflammatory condition of unknown etiology that can affect the eye. The most common ocular manifestation related to VKH is bilateral diffuse uveitis associated to exudative retinal detachment. Although these patients respond well to steroid pulse therapy, we report a case of a 44-year-old female patient presenting bilateral exudative retinal detachment and clinical diagnosis of VKH, who did not respond to the first cycle of 3-day pulse therapy with methylprednisolone. The exudation was reabsorbed only after a second cycle of steroid therapy.