Document details

Correlation between microdilution, Etest, and disk diffusion methods for antifungal susceptibility testing of fluconazole against Candida sp. blood isolates

Author(s): Menezes,Everardo Albuquerque ; Vasconcelos Júnior,Antônio Alexandre de ; Ângelo,Maria Rozzelê Ferreira ; Cunha,Maria da Conceição dos Santos Oliveira ; Cunha,Francisco Afrânio

Date: 2013

Origin: Oasisbr

Subject(s): Disk diffusion; Antifungal susceptibility; Fluconazole


Description

INTRODUCTION: Antifungal susceptibility testing assists in finding the appropriate treatment for fungal infections, which are increasingly common. However, such testing is not very widespread. There are several existing methods, and the correlation between such methods was evaluated in this study. METHODS: The susceptibility to fluconazole of 35 strains of Candida sp. isolated from blood cultures was evaluated by the following methods: microdilution, Etest, and disk diffusion. RESULTS: The correlation between the methods was around 90%. CONCLUSIONS: The disk diffusion test exhibited a good correlation and can be used in laboratory routines to detect strains of Candida sp. that are resistant to fluconazole.

Document Type Journal article
Language English
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