Autor(es): Guerreiro,Gisleine ; Lima,Janete Eliza S. de ; Fernandes,João Batista ; Silva,M. Fátima das G. F. da ; Vieira,Paulo Cezar ; Magalhães,Claudia Maria I. ; Pagnocca,Fernando Carlos ; Bueno,Odair Corrêa ; Hebling,Maria José Aparecida ; Pirani,José Rubens
Data: 2005
Origem: Oasisbr
Assunto(s): Pilocarpus riedelianus; sesquiterpenes; antimicrobial activity
Pilocarpus riedelianus was studied in order to obtain compounds with activity against fungi and bacteria. The dichloromethane extract, the most active one, was chromatographed yielding hexane and dichloromethane fractions. Six known sesquiterpenes, alpha-calacorene, beta-calacorene, gamma-calacorene, cadalene, sesquichamaenol and 1-hydroxy-1,3,5-bisabolatrien-10-one were identified in the hexane fractions. The identification of these compound was done by NMR and GC/MS analyses. The hexane fraction from the dichloromethane extract showed activity against several fungi and bacteria.
