Author(s): Gomes,Regina Ferreira ; Santos,Hélcio Silva dos ; Albuquerque,Maria Rose Jane R. ; Pessoa,Otília Deusdênia L. ; Lotufo,Leticia V. Costa ; Pessoa,Claudia do Ó ; Moraes,Manoel Odorico de ; Rodrigues,Felipe A. R.
Date: 2010
Origin: Oasisbr
Subject(s): Blainvillea rhomboidea; Asteraceae; flavonoids
The phytochemical investigation of the ethanol extract from the aerial parts of Blainvillea rhomboidea (Asteraceae) resulted in the isolation and characterization of 8β-tigloyloxy-grazielia acid, together with the flavonoids derrone, acacetin, luteolin and luteolin 7-methyl ether, and p-(1-methyl-ethan-1-ol)-phenol. The structures of all compounds were determined by spectroscopic methods (¹H and 13C NMR and HREIMS) and comparison with published spectral data. The flavonoids luteolin and 7-O-metyl-luteolin, isolated from the active dichloromethane fraction, showed moderate cytotoxic activity.
