Author(s): Silva,Márcia de Oliveira ; Oliveira,Patrick Vanttinny Vieira de ; Vale,Pedro Henrique Cavalcante ; Cunha,Rinadja de Melo ; Lages,Joyce Santos ; Brito,Dyego José de Araújo ; Salgado Filho,Natalino ; Guedes,Felipe Leite ; Silva,Gyl Eanes Barros ; Santos,Ricardo Ferreira
Date: 2021
Origin: Oasisbr
Subject(s): Lupus Erythematosus, Systemic; Lupus Nephritis; Fluorescent Antibody Technique.
Abstract Systemic lupus erythematosus (SLE) is a chronic multisystem autoimmune inflammatory disease. However, some patients may exhibit a histological pattern of kidney injury, with characteristics indistinguishable from lupus nephritis, but without presenting any extrarenal symptoms or serologies suggestive of SLE. Such involvement has recently been called non-lupus full-house nephropathy. The objective is to report a series of clinical cases referred to the Laboratory of the Federal University of Maranhão that received the diagnosis of "full-house" nephropathy unrelated to lupus, upon immunofluorescence and to discuss its evolution and outcomes. Non-lupus full-house nephropathy represents a diagnostic and therapeutic challenge, because it is a new entity, which still needs further studies and may be the initial manifestation of SLE, isolated manifestation of SLE or a new pathology unrelated to SLE.
