Initial antimicrobial activity studies of plants of the riverside forests of the southern Uruguay River

• Autor(es): Bertucci,Ana ; Olivaro,Cristina ; Silva,Pedro Almeida da ; Ramos,Daniela ; Cerdeiras,Maria Pia ; Vázquez,Alvaro
• Data: 2009
• Origem: Oasisbr
• Assunto(s): Antimicrobial activity; bioprospection; Mycobacterium; Candida
• Tipo de Documento: Artigo científico
• Idioma: Inglês

Descrição

Development of new antimicrobial compounds against different microorganisms is becoming critically important, as infectious diseases are still one of the leading causes of death in the world. Plants can be a useful source of these lead compounds. In this study, 66 extracts of 25 plants of the riverside forest of southern Uruguay River were studied for antimicrobial activity against Staphylococcus aureus, Listeria inocua, Escherichia coli, Pseudomonas aeruginosa, Mycobacterium tuberculosis, Aspergillus niger and Candida albicans. Fifty-three of these extracts showed some kind of antimicrobial activity. Six of these (Eugenia mansoni, Eugenia repanda, Myrcianthes cisplatensis, Paullinia ellegans, Petunia sp and Ruprechtia laxiflora) presented activity against Mycobacterium tuberculosis with MIC values as low as 50 μg/mL.