Design and production of sintered β-tricalcium phosphate 3D scaffolds for bone tissue regeneration

• Author(s): Santos, Carlos Filipe Lopes ; Silva, Abílio P. ; Lopes, Luís ; Pires, Inês ; Correia, Ilídio Joaquim Sobreira
• Date: 2012
• Persistent ID: http://hdl.handle.net/10400.6/4633
• Origin: uBibliorum
• Subject(s): β-TCP scaffolds; Bone regeneration; Computer Aided Tissue Engineering; Individualized scaffolds; Rapid prototyping
• Document Type: Journal article
• Language: English
• Contributor(s): uBibliorum

Description

The characteristics of sintered β-tricalcium phosphate (β-TCP) scaffolds produced by 3D printing were studied by means of X-ray diffraction, Scanning Electron Microscopy, Fourier transform infrared spectroscopy, uniaxial compression tests and cytotoxicity tests, using human osteoblast cells. The results reported include details of the β-TCP scaffolds' porosity, density, phase stability, mechanical behavior and cytotoxic profile. Collectively, these properties are fundamental for the future application of these scaffolds as bone substitutes for individualized therapy.