Autor(es):
Douine, Maylis ; Bonifay, Timotheé ; Lambert, Yann ; Mutricy, Louise ; Galindo, Muriel Suzanne ; Godin, Audrey ; Bourhy, Pascale ; Picardeau, Mathieu ; Saout, Mona ; Demar, Magalie ; Sanna, Alice ; Mosnier, Emilie ; Blaizot, Romain ; Couppie´, Pierre ; Nacher, Mathieu ; Adenis, Antoine ; Suarez-Mutis, Martha ; Vreden, Stephen ; Epelboin, Loïc ; Schaub, Roxane
Data: 2022
Origem: Oasisbr
Assunto(s): Zoonoses; Mineração de ouro; EStudo corte transversal; Imunização da febre amarela; Leptospirose; Leishmaniose; População que trabalha na mineração ilegal; Guiana Francesa; Q febre; Zoonoses; Gold mining; Cross-sectional study; Yellow fever immunization; Q fever; Leptospirosis; Leishmaniasis; Population working on illegal mining; French Guiana
Descrição
Centre d’Investigation Clinique Antilles-Guyane (Inserm 1424), Centre Hospitalier de Cayenne, Cayenne, French Guiana / TBIP, Université de la Guyane, Cayenne, French Guiana / Centre de Ressources Biologiques Amazonie, Cayenne, French Guiana.
Centre d’Investigation Clinique Antilles-Guyane (Inserm 1424), Centre Hospitalier de Cayenne, Cayenne, French Guiana.
Centre d’Investigation Clinique Antilles-Guyane (Inserm 1424), Centre Hospitalier de Cayenne, Cayenne, French Guiana.
Centre d’Investigation Clinique Antilles-Guyane (Inserm 1424), Centre Hospitalier de Cayenne, Cayenne, French Guiana.
Centre d’Investigation Clinique Antilles-Guyane (Inserm 1424), Centre Hospitalier de Cayenne, Cayenne, French Guiana.
Centre d’Investigation Clinique Antilles-Guyane (Inserm 1424), Centre Hospitalier de Cayenne, Cayenne, French Guiana.
National Reference Center for Leptospirosis, Biology of Spirochetes unit, Institut Pasteur, Paris, France.
National Reference Center for Leptospirosis, Biology of Spirochetes unit, Institut Pasteur, Paris, France.
TBIP, Universite´ de la Guyane, Cayenne, French Guiana.
TBIP, Universite´ de la Guyane, Cayenne, French Guiana / University Laboratory of Mycology-Parasitology, Centre Hospitalier de Cayenne, Cayenne, French Guiana.
Centre d’Investigation Clinique Antilles-Guyane (Inserm 1424), Centre Hospitalier de Cayenne, Cayenne, French Guiana.
Delocalized Health Centers, Centre Hospitalier de Cayenne, Cayenne, French Guiana.
TBIP, Universite´ de la Guyane, Cayenne, French Guiana / Department of Dermatology, Centre Hospitalier de Cayenne, Cayenne, French Guiana.
TBIP, Université de la Guyane, Cayenne, French Guiana / Department of Dermatology, Centre Hospitalier de Cayenne, Cayenne, French Guiana.
Centre d’Investigation Clinique Antilles-Guyane (Inserm 1424), Centre Hospitalier de Cayenne, Cayenne, French Guiana / TBIP, Université de la Guyane, Cayenne, French Guiana / Centre de Ressources Biologiques Amazonie, Cayenne, French Guiana.
Centre d’Investigation Clinique Antilles-Guyane (Inserm 1424), Centre Hospitalier de Cayenne, Cayenne, French Guiana / TBIP, Université de la Guyane, Cayenne, French Guiana / Centre de Ressources Biologiques Amazonie, Cayenne, French Guiana.
Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Doenças Parasitárias. Rio de Janeiro, RJ, Brasil.
Foundation for Scientific Research Suriname, Paramaribo, Suriname.
Centre d’Investigation Clinique Antilles-Guyane (Inserm 1424), Centre Hospitalier de Cayenne, Cayenne, French Guiana / TBIP, Université de la Guyane, Cayenne, French Guiana / Infectious and Tropical Diseases Unit, Centre Hospitalier de Cayenne, Cayenne, French Guiana.
Centre d’Investigation Clinique Antilles-Guyane (Inserm 1424), Centre Hospitalier de Cayenne, Cayenne, French Guiana / TBIP, Université de la Guyane, Cayenne, French Guiana.
Background Most emerging pathogens are zoonoses and have a wildlife origin. Anthropization and disruption of ecosystems favor the crossing of inter-species barriers. We hypothesize that the marginalized population of undocumented goldminers in the Amazon is at risk of acquiring zoonoses. Method A multicentric cross-sectional study included consenting gold-mining adult workers in 2019. A clinical examination recorded dermatological signs of leishmaniosis and past history of yellow fever vaccination. Biological tests were performed for yellow fever, Q fever and leptospirosis serologies. Additional blood samples from a previous study in 2015 were also tested Results In 2019, 380 individuals were included in the study, along with 407 samples from the 2015 biological collection. The seroprevalence of leptospirosis was 31.0% [95%CI = 26.4–35.5] in 2015 and 28.1% [23.5–32.7] in 2019. The seroprevalence of Q fever was 2.9% [1.2–4.6]. The majority of participants reported being vaccinated against yellow fever (93.6%) and 97.9% had seroneutralizing antibodies. The prevalence of suspected active mucocutaneous leishmaniasis was 2.4% [0.8–3.9]. for leptospirosis.
