Author(s): Diniz, A. R. ; Borrego, P. ; Bártolo, I. ; Taveira, N.
Date: 2015
Persistent ID: http://hdl.handle.net/10400.26/15091
Origin: Egas Moniz - Cooperativa de Ensino Superior, CRL
Project/scholarship: info:eu-repo/grantAgreement/FCT/3599-PPCDT/122400/PT ; info:eu-repo/grantAgreement/FCT/3599-PPCDT/123654/PT ; info:eu-repo/grantAgreement/FCT/SFRH/SFRH%2FBD%2F89140%2F2012/PT;
Subject(s): HIV cell-to-cell fusion; Antiretroviral drugs; Neutralizing antibodies
Poster presented at the 7th iMed.ULisboa Postgraduate Students Meeting. Lisbon, 15 July 2015
"Inhibition of HIV cell entry by antiretroviral drugs and neutralizing antibodies (NAbs) is typically measured in assays where cell-free virions enter reporter cell lines. However, direct Env-mediated cell-to-cell transmission is a major mechanism of HIV infection that also needs to be targeted. In this work we aimed to determine the ability of anti-HIV compounds in clinical or research use to inhibit HIV mediated cell-to-cell fusion (syncytia formation)."
Fundação para a Ciência e a Tecnologia - Portugal ; European Union
