Document details

Volumetric alterations in the nucleus accumbens and caudate nucleus in bulimia nervosa: a structural magnetic resonance imaging study

Author(s): Coutinho, Joana ; Ramos, Ana Filipa Pereira ; Maia, Liliana Filipa Costa ; Castro, Liliana Correia de ; Conceição, Eva Martins da ; Geliebter, Allan ; Machado, Paulo P. P. ; Gonçalves, Óscar F. ; Sampaio, Adriana

Date: 2015

Persistent ID:

Origin: RepositóriUM - Universidade do Minho

Project/scholarship: info:eu-repo/grantAgreement/FCT/5876-PPCDTI/99981/PT ;

Subject(s): Adult; Binge-eating disorder; Brain diseases; Bulimia nervosa; Case-control studies; Caudate nucleus; Female; Humans; Magnetic resonance imaging; Nucleus accumbens; Organ size; manual segmentation; Social Sciences; Science & Technology; Social Sciences; Social Sciences; Science & Technology; Science & Technology


Bulimia nervosa (BN) is an eating disorder characterized by recurrent episodes of binge eating and inappropriate compensatory behaviors (such as purging, fasting, or excessive exercise) to prevent weight gain. BN has been associated with deficits in inhibitory control processes. The basal ganglia specifically, the nucleus accumbens (NAc) and the caudate nucleus (CN) are part of the frontostriatal circuits involved in inhibitory control. The main goal of this study was to investigate the presence of morphological alterations in the NAc and the CN in a sample of patients diagnosed with BN.

Document Type Research article
Language English
Contributor(s) Coutinho, Joana; Ramos, Ana Filipa Pereira; Maia, Liliana Filipa Costa; Castro, Liliana Correia de; Conceição, Eva Martins da; Geliebter, Allan; Machado, Paulo P. P.; Gonçalves, Óscar F.; Sampaio, Adriana
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