Author(s): Ferreira, AF. ; Vecino, Xanel ; Ferreira, Débora ; Cruz, J. M. ; Moldes, A. B. ; Rodrigues, L. R.
Date: 2017
Persistent ID: http://hdl.handle.net/1822/47697
Origin: RepositóriUM - Universidade do Minho
Project/scholarship: info:eu-repo/grantAgreement/FCT/5876/147337/PT; info:eu-repo/grantAgreement/FCT/5876-PPCDTI/126270/PT ; info:eu-repo/grantAgreement/FCT/COMPETE/126270/PT;
Subject(s): Biosurfactant; Essential oils; Antioxidants; Emulsions; Skin; Cells.; Science & Technology
Cosmetic and personal care products including toothpaste, shampoo, creams, makeup, among others, are usually formulated with petroleum-based surfactants, although in the last years the consume trend for green products is inducing the replacement of surface-active agents in these formulations by natural surfactants, so-called biosurfactants. In addition to their surfactant capacity, many biosurfactants can act as good emulsifiers, which is an extra advantage in the preparation of green cosmetic products. In this work, a biosurfactant obtained from Lactobacillus paracasei was used as a stabilizing agent in oil-in-water emulsions containing essential oils and natural antioxidant extract. In the presence of biosurfactant, maximum percentages of emulsion volumes (EV = 100%) were observed, with droplets sizes about 199 nm. These results were comparable with the ones obtained using sodium dodecyl sulfate (SDS), a synthetic well known surfactant with high emulsify capacity. Moreover, the biosurfactant and emulsions cytotoxicity was evaluated using a mouse fibroblast cell line. Solutions containing 5 g/L of biosurfactant presented cell proliferation values of 97%, whereas 0.5 g/L of SDS showed a strong inhibitory effect. Overall, the results herein gathered are very promising towards the development of new green cosmetic formulations.
This study was supported by the Portuguese Foundation for Science and Technology (FCT) under the scope of the strategic funding of UID/BIO/04469/2013 unit, COMPETE 2020 (POCI-01-0145-FEDER-006684) and the project RECI/BBB-EBI/0179/2012 (FCOMP-01-0124-FEDER-027462), as well as X. Vecino post-doctoral grant (SFRH/BPD/101476/2014). Additionally, the authors acknowledge the financial support from Spanish Ministry of Economy and Competitiveness (FEDER funds) under the project CTM2015-68904. Also, A. Ferreira acknowledges to the Region Aquitaine Limousin Poitou-Charentes for her Erasmus + internship.
info:eu-repo/semantics/publishedVersion
