Project/scholarship details


  • Funder

    FCT - Fundação para a Ciência e a Tecnologia, I.P.

  • Funder's country

    Portugal

  • Funding program

    5876-PPCDTI

  • Funding amount

    188,000.00 €

  • Start date

    2010-04-01

  • End date

    2013-09-30

Documents


Draft genome sequences of two pseudomonas aeruginosa clinical isolates with dif...

Castro, Pedro Soares; Marques, Diana; Demyanchuk, S.; Faustino, A.; Santos, P. M.

Pseudomonas aeruginosa is a primary cause of opportunistic infections. We have sequenced and annotated the genomes of two P. aeruginosa clinical isolates evidencing different antibiotic susceptibilities. Registered differences in the composition of their accessory genomes may provide clues on P. aeruginosa strategies to thrive in different environments like infection loci.; PTDC/EBB-BIO/104980/2008, Foundation ...


Towards the description of the genome aatalogue of Pseudomonas sp. Strain M1

Castro, Pedro Miguel Soares; Santos, Pedro M.

Pseudomonas sp. strain M1 is a soil isolate with remarkable biotechnological potential. The genome of Pseudomonas sp. M1 was sequenced using both 454 and Illumina technologies. A customized genome assembly pipeline was used to reconstruct its genome sequence to a single scaffold.; This work was supported by FEDER through POFC—COMPETE and by national funds from FCT through the projects PEst-C/BIA/UI4050/2011 and...


Deciphering the genome repertoire of Pseudomonas sp. M1 toward β-Myrcene biotra...

Castro, Pedro Miguel Soares; Santos, Pedro M.

Pseudomonas sp. M1 is able to mineralize several unusual substrates of natural and xenobiotic origin, contributing to its competence to thrive in different ecological niches. In this work, the genome of M1 strain was resequenced by Illumina MiSeq to refine the quality of a published draft by resolving the majority of repeat-rich regions. In silico genome analysis led to the prediction of metabolic pathways invo...


Optimization of Pseudomonas sp. M1 as a biocatalyst of β-myrcene and related pl...

Castro, Pedro Miguel Soares

Tese de Doutoramento em Biologia Molecular e Ambiental (Especialização em Biotecnologia Molecular); Several monoterpenes (e.g. β-myrcene) have a great industrial potential due to their organoleptic and therapeutic properties. However, monoterpene exploitation as industrially-relevant molecules is often limited because of their intricate properties (e.g. high hydrophobicity and structural instability). Biocataly...

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