Project/scholarship details


  • Funder

    FCT - Fundação para a Ciência e a Tecnologia, I.P.

  • Funder's country

    Portugal

  • Funding program

    5876-PPCDTI

  • Funding amount

    188,726.00 €

  • Start date

    2011-01-01

  • End date

    2013-12-31

Documents


Innovative self-assembled and microfabricated structures to be used in distinct...

Mendes, Ana Carina

Tese de doutoramento em Engenharia Biomédica; Advances in self-assembly offer new opportunities in molecular design of biomaterials. A major advantage of these systems is their ability to generate similar fibrillar structures to those found in the natural extracellular matrix (ECM) of tissues and to integrate directly into their structure biomolecular ligands for cell signalling. On the other hand, the integrat...


Molecularly designed self-assembling matrices for applications in regenerative ...

Ferreira, Daniela Sofia Dias

Programa Doutoral em Engenharia dos Tecidos, Medicina Regenerativa e Células Estaminais.; The exquisite field of molecular self-assembly (SA) offers numerous opportunities to fabricate biomaterials with increased level of precision and complexity. Peptide molecules have been widely used as building blocks in biomaterial SA as they provide the possibility to form nanofibers that resemble the filamentous structur...


Co-assembly, spatiotemporal control and morphogenesis of a hybrid protein-pepti...

Inostroza-Brito, K. E.; Collin, E.; Siton-Mendelson, O.; Smith, K. H.; Monge-Marcet, A.; Ferreira, D. S.; Rodríguez, R. P.; Alonso, M.

Controlling molecular interactions between bioinspired molecules can enable the development of new materials with higher complexity and innovative properties. Here we report on a dynamic system that emerges from the conformational modification of an elastin-like protein by peptide amphiphiles and with the capacity to access, and be maintained in, non-equilibrium for substantial periods of time. The system enabl...


Phage display technology in biomaterials engineering: progress and opportunitie...

Martins, Ivone M.; Reis, R. L.; Azevedo, Helena S.

The Supporting Information is available free of charge on the ACS Publications website at DOI: 10.1021/acschembio.5b00717. Table S1 shows the follow-up analysis on the subsequent applications of peptide sequences listed in Table 1 (PDF).; The field of regenerative medicine has been gaining momentum steadily over the past few years. The emphasis in regenerative medicine is to use various in-vitro and in-vivo app...

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