Project/scholarship details


  • Funder

    FCT - Fundação para a Ciência e a Tecnologia, I.P.

  • Funder's country

    Portugal

  • Funding program

    3599-PPCDT

  • Funding amount

    80,000.00 €

  • Start date

    Tue Mar 01 00:00:00 WET 2011

  • End date

    Sun Aug 31 00:00:00 WEST 2014

  • Date awarded

    Tue Jun 14 00:00:00 WEST 2011

Documents


Impact of Loci Nature on Estimating Recombination and Mutation Rates in Chlamyd...

Ferreira, Rita; Borges, Vítor; Nunes, Alexandra; Nogueira, Paulo; Borrego, Maria José; Gomes, João Paulo

The knowledge of the frequency and relative weight of mutation and recombination events in evolution is essential for understanding how microorganisms reach fitted phenotypes. Traditionally, these evolutionary parameters have been inferred by using data from multilocus sequence typing (MLST), which is known to have yielded conflicting results. In the near future, these estimations will certainly be performed by...

Date: 2012   |   Origin: Direção-Geral da Saúde

Identification of type III secretion substrates of Chlamydia trachomatis using ...

da Cunha, Maria; Milho, Catarina; Almeida, Filipe; Pais, Sara; Borges, Vitor; Mauricio, Rui; Borrego, Maria; Gomes, João; Mota, Luis

BACKGROUND:Chlamydia trachomatis is an obligate intracellular human pathogen causing ocular and urogenital infections that are a significant clinical and public health concern. This bacterium uses a type III secretion (T3S) system to manipulate host cells, through the delivery of effector proteins into their cytosol, membranes, and nucleus. In this work, we aimed to find previously unidentified C. trachomatis T...

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