Project/scholarship details
- Project/scholarship ID
125883
- Reference
PTDC/DTP-FTO/1057/2012
- FundRef URI
- Funder
FCT - Fundação para a Ciência e a Tecnologia, I.P.
- Funder's country
Portugal
- Funding program
3599-PPCDT
- Funding amount
144,168.00 €
- Start date
2013-04-01
- End date
2015-12-31
Documents
Evaluation of the ability of powdered milk to produce mini-tablets to deliver p...
Pinto, Joana T.; Brachkova, Mariya; Fernandes, Ana I.; Pinto, João F.Paper presented at the 7th International Granulation Workshop. 1-3 July 2015, University of Sheffield, UK; "This work aims to evaluate the usefulness of powdered milk as a vehicle of drugs for direct compression into mini-tablets specifically designed for the pediatric population. A 23 full factorial design was carried out to identify the effect of selected variables and their interactions (paracetamol to milk ...
Medicinal powders made of fresh milk for pediatric use
Aguiar, J. P.; Fernandes, T.; Nese, C.; Pinto, J. F.; Fernandes, A. I.Communication presented at the 1st International Congress of CiiEM - From Basic Sciences to Clinical Research. 27-28 November 2015, Egas Moniz, Caparica, Portugal; "Nowadays, the need to formulate medicines specifically designed for children is imperative [1] and solid dosage forms are the first choice for providing the required drug stability and dose accuracy. Milk, as a worldwide accepted food, is proposed i...
Development of casein micellar pediatric formulations
Brachkova, M. I.; Pinto, J. T.; Fernandes, A. I.; Pinto, J. F.Poster presented at the 1st European Conference on Pharmaceutics. 13-14 April 2015, Reims, France.; "The current need for medicines specifically designed for children, which consider ease of administration, dose flexibility, palatability, safety of excipients, stability and therapeutic equivalency of pediatric dosage forms, has driven the development of pediatric drug formulations. In the present work casein (C...
Effect of different excipients and processing conditions on casein micellar for...
Brachkova, Mariya; Pinto, Joana T.; Fernandes, Ana I.; Pinto, João F.Poster presented at the AAPS Annual Meeting and Exposition (American Association of Pharmaceutical Scientists). October 25-29, 2015, Orlando (FL), USA; "Purpose: Investigation of the potential of casein micellar formulations as drug vehicles in pediatrics."; Fundação para a Ciência e a Tecnologia (PTDC/DTP-FTO/1057/2012)
Evaluation of the ability of powdered milk to produce mini-tablets containing p...
Pinto, J. T.; Brachkova, M. I.; Fernandes, A. I.; Pinto, J. F.Poster presented at the 1st European Conference on Pharmaceutics. 13-14 April 2015, Reims, France; "In recent years the development of medicines for paediatric use have gained increase interest. Small, flexible solid dosage forms, such as mini-tablets, are an attractive choice when developing new medicines for children. Excipients, though innocuous in adults, may pose a threat to the different paediatric age gr...
HPLC determination of theophylline and paracetamol in fresh and powdered milk
Fernandes, T.; Aguiar, J.; Pinto, J. F.; Fernandes, A. I.Poster presented at the 1st International Congress of CiiEM - From Basic Sciences to Clinical Research. 27-28 November 2015, Egas Moniz, Caparica, Portugal; "Theophylline and paracetamol are drugs used worldwide both in human and veterinary medicine. Paracetamol (or acetaminophen) is employed as analgesic and antipyretic, and theophylline is a bronchodilator drug used in the treatment of asthma and chronic obst...
Simple and sensitive HPLC determination of paracetamol and theophylline in fres...
Fernandes, T. A.; Aguiar, J. P.; Fernandes, A. I.; Pinto, J. F.Poster presented at the 10th World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology. 4-7 April 2016, Glasgow, UK
Spray-dried fresh milk powders for oral drug delivery in pediatrics
Aguiar, J. P.; Fernandes, T. A.; Nese, C.; Fernandes, A. I.; Pinto, J. F.Poster presented at the 10th World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology. 4-7 April 2016, Glasgow, UK
Evaluation of the ability of powdered milk to produce minitablets containing pa...
Pinto, Joana T.; Brachkova, Maryia I.; Fernandes, Ana I.; Pinto, João F.The work aims at evaluating the usefulness of powdered milk as a drug matrix for the production of minitablets specifically designed for children. Mixtures made of powdered milk, paracetamol, mannitol, sodium croscarmellose and magnesium stearate (evaluated for flow properties, cohesiveness and caking tendency) were compacted into beams (evaluated for deformation, elasticity and stiffness) and minitablets (eval...
Child-driven design of milk micelles for drug delivery
Fernandes, T.; Aguiar, J.; Scheppe, S.; Pinto, J. F.; Fernandes, A. I.Poster presented at the 9th EuPFI Conference [European Paediatric Formulation Initiative], 19-21th Sep 2017, Warsaw, Poland
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