Project/scholarship details


  • Funder

    FCT - Fundação para a Ciência e a Tecnologia, I.P.

  • Funder's country

    Portugal

  • Funding program

    5876-PPCDTI

  • Funding amount

    338,852.00 €

  • Start date

    2013-01-01

  • End date

    2015-12-31

Documents


Layer-by-layer technique to developing functional nanolaminate films with antif...

Fabra, María José; Flores-López, M. L.; Cerqueira, M. A.; Jasso de Rodríguez, D.; Lagaron, J. M.; Vicente, A. A.

The layer-by-layer (LbL) deposition method was used to build up alternating layers (five) of different polyelectrolyte solutions (alginate, zein-carvacrol nanocapsules, chitosan and chitosan-carvacrol emulsions) on an aminolysed/charged polyethylene terephthalate (A/C PET) film. These nanolaminated films were characterised by contact angle measurements and through the determination of water vapour (WVTR) and ox...


The cystic fibrosis microbiome in an ecological perspective and its impact in a...

Magalhães, Andreia; Azevedo, Nuno F.; Pereira, Maria Olívia; Lopes, Susana Patrícia

The recent focus on the cystic fibrosis (CF) complex microbiome has led to the recognition that the microbes can interact between them and with the host immune system, affecting the disease progression and treatment routes. Although the main focus remains on the interactions between traditional pathogens, growing evidence supports the contribution and the role of emergent species. Understanding the mechanisms a...


A design of experiments to assess phosphorous removal and crystal properties in...

Barbosa, S. G.; Peixoto, L.; Meulman, Brendo; Alves, M. M.; Pereira, M. A.

Phosphorus recycling and recovery has received special attention due to its non-replaceable and non-renewability. Phosphorus recovery from human urine in the form of struvite crystals is a potential alternative source. In this work, the efficiency of struvite precipitation from source separated human urine and struvite crystals size were analyzed using three different Mg2+ sources (MgCl2, Mg(OH)2 and MgO), indi...


In vivo imaging of glycol chitosan-based nanogel biodistribution

Pereira, Paula; Correia, Alexandra; Gama, F. M.

The preclinical development of nanomedicines raises several challenges and requires a comprehensive characterization. Among them is the evaluation of the biodistribution following systemic administration. In previous work, the biocompatibility and in vitro targeting ability of a glycol chitosan (GC) based nanogel have been validated. In the present study, its biodistribution in the mice is assessed, using near-...


Short-and long-term exposure to heavy metals induced oxidative stress response ...

Machado, Manuela D.; Soares, Eduardo V.

Algal cells can be exposed to toxicants for a short term due to accidental discharges or, more commonly, for a long term. The present work aimed to assess the ability of Cd, Cr, Cu and Zn to induce accumulation of reactive oxygen species (ROS) in the alga Pseudokirchneriella subcapitata after a short (6?h) or a long (72?h) exposure time. The relationship between the ROS induction and the content of reduced glut...


Microbial remediation of organometals and oil hydrocarbons in the marine enviro...

Cruz, Andreia; Cavaleiro, Ana Júlia; Paulo, Ana M. S.; Louvado, António; Alves, M. M.; Almeida, Adelaide; Cunha, Ângela

Marine environments are exposed to pollution that mostly results from human activities. Organometals and oil hydrocarbons are among the most hazardous pollutants. In surface waters and along the water column, these compounds are more easily degraded than in sediments, especially under anoxic conditions, where they are highly persistent. Due to their negative impact in living organisms, decontamination of pollut...


Biorefinery approach for the valorization of vine pruning residue

Jesus, M. S.; Romani, Aloia Perez; Domingues, Lucília; Teixeira, J. A.

Lignocellulosic biomass (namely vine pruning residue, VPR) conversion into biofuels is considered a promising alternative to replace fossil fuels. In this work, VPR was submitted to hydrothermal treatment under isothermal conditions (180 and 200oC for 10-90min), in order to assess the effect of the treatment on the VPR fractionation. Liquid phase was analyzed for oligosaccharides composition and solid phase was...


Biotechnological approaches of crude glycerol use: optimization of citric acid ...

Ferreira, Patrícia Marlene Alves

The increase of biodiesel production results in an accumulation of crude glycerol, the main byproduct from biodiesel industry. To take advantage of the glycerol surplus, many biotechnological processes are being studied. Crude glycerol can be used as carbon source to produce citric acid by Yarrowia lipolytica under nitrogen-limited growth conditions. However, other operational and medium conditions directly aff...


Valorizing recycled paper sludge by a bioethanol production process with cellul...

Gomes, Daniel Gonçalves; Domingues, Lucília; Gama, F. M.

The feasibility of cellulase recycling in the scope of bioethanol production from recycled paper sludge (RPS), an inexpensive byproduct with around 39% of carbohydrates, is analyzed. RPS was easily converted and fermented by enzymes and cells, respectively. Final enzyme partition between solid and liquid phases was investigated, the solid-bound enzymes being efficiently recovered by alkaline washing. RPS hydrol...


In vitro behaviour of curcumin nanoemulsions stabilized by biopolymer emulsifie...

Pinheiro, A. C.; Coimbra, Manuel A.; Vicente, A. A.

Nanoemulsions present a high potential to be used in food products due to their advantages over conventional emulsions (e.g. higher stability to gravitational separation and droplet aggregation and enhanced bioavailability of encapsulated compounds), however their application to foods is hindered by some concerns about potential risks associated with their ingestion. The knowledge of the behaviour of nanoemulsi...

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