Project/scholarship details
- Project/scholarship ID
126270
- Reference
RECI/BBB-EBI/0179/2012
- FundRef URI
- Funder
FCT - Fundação para a Ciência e a Tecnologia, I.P.
- Funder's country
Portugal
- Funding program
5876-PPCDTI
- Funding amount
338,852.00 €
- Start date
2013-01-01
- End date
2015-12-31
Documents
Structural and mechanical properties of organogels: Role of oil and gelator mol...
Cerqueira, Miguel Ângelo Parente Ribeiro; Fasolin, Luiz H.; Picone, Carolina S. F.; Pastrana, Lorenzo M.; Cunha, Rosiane L.; Vicente, A. A.Supplementary data to this article can be found online at http://dx.doi.org/10.1016/j.foodres.2017.03.021.; This work aims at evaluating the influence of oil and gelator structure on organogels' properties through rheological measurements, polarized microscopy and small-angle X-ray scattering (SAXS). Four different food-grade gelators (glyceryl tristearate GT; sorbitan tristearate ST; sorbitan monostearate SM a...
Peptideprotein interactions within human hair keratins
Cruz, Célia F.; Azoia, Nuno G.; Matamá, Teresa; Cavaco-Paulo, ArturWe selected 1235 decapeptides from human hair proteins encoded by human genes of keratins and keratin associated proteins. The peptides were linked to glass arrays and screened for their affinity towards a solution of human hair extracted keratin fraction. Based on the physicochemical properties of the peptides, ten variables were studied: content of different types of amino acid side chains (cysteine, hydropho...
Influence of nutritional and operational parameters on the production of butano...
Marusich, R.; Alves, M. M.; Rodrigues, L. R.Butanol and 1,3-propanediol (1,3-PDO) are simultaneously produced by Clostridium pasteurianum from glycerol. In this study, random chemical mutagenesis of C. pasteurianum DSM 525 was conducted to improve its tolerance to butanol. Selected nutritional and operational parameters were evaluated to identify strategies that favour the production of each metabolite. From those experiments, it was possible to isolate ...
Candida glabrata biofilms: How far have we come?
Rodrigues, Célia Fortuna; Rodrigues, Maria Elisa Costa; Silva, Sónia Carina; Henriques, MarianaInfections caused by Candida species have been increasing in the last decades and can result in local or systemic infections, with high morbidity and mortality. After Candida albicans, Candida glabrata is one of the most prevalent pathogenic fungi in humans. In addition to the high antifungal drugs resistance and inability to form hyphae or secret hydrolases, C. glabrata retain many virulence factors that contr...
Carbon nanotubes accelerate methane production in pure cultures of methanogens ...
Salvador, Andreia F.; Martins, Gilberto; Melle-Franco, Manuel; Serpa, Ricardo; Stams, Alfons Johannes Maria; Cavaleiro, Ana Júlia; Pereira, M. AlcinaCarbon materials have been reported to facilitate direct interspecies electron transfer (DIET) between bacteria and methanogens improving methane production in anaerobic processes. In this work, the effect of increasing concentrations of carbon nanotubes (CNT) on the activity of pure cultures of methanogens and on typical fatty acid-degrading syntrophic methanogenic coculture was evaluated. CNT affected methane...
Substrate inhibition of uracil phosphoribosyltransferase (UPRT) in distinct mic...
Aguiar, Tatiana Quinta; Silva, Rui; Oliveira, Carla; Domingues, LucíliaMicrobiotec'17 - Congress of Microbiology and Biotechnology 2017; Background: Unlike the established practice, the supply of exogenous uracil cannot fully rescue uracil auxotrophy in Ura- mutants of some species of industrial and/or medical significance (e.g. Ashbya gossypii, Candida guilliermondii, C. albicans, Leishmania donovani), which require uridine for proper growth [1-4]. Here we reveal the molecular me...
Physicochemical study of biomolecular interactions between lysosomotropic surfa...
Janek, Tomasz; Czyznikowska, Zaneta; Luczynski, Jacek; Gudiña, Eduardo J.; Rodrigues, L. R.; Galezowska, JoannaThe interactions between two cationic lysosomotropic surfactants (2-dodecanoyloxyethyl)trimethylammonium bromide (DMM-11) and (2-dodecanoyloxypropyl)trimethylammonium bromide (DMPM-11) with bovine serum albumin (BSA) in Hepes buffer (pH = 7.4) were systematically studied by surface tension, fluorescence and circular dichroism (CD) spectroscopy and isothermal titration calorimetry (ITC). Furthermore, the size of...
Sodium lauryl ether sulfate (SLES) degradation by nitrate-reducing bacteria
Paulo, Ana M. S.; Aydin, Rozelin; Dimitrov, Mauricio R.; Vreeling, Harm; Cavaleiro, Ana Júlia; García-Encina, Pedro A.; Stams, Alfons Johannes MariaThe online version of this article (doi:10.1007/s00253-017-8212-x) contains supplementary material, which is available to authorized users.; The surfactant sodium lauryl ether sulfate (SLES) is widely used in the composition of detergents and frequently ends up in wastewater treatment plants (WWTPs). While aerobic SLES degradation is well studied, little is known about the fate of this compound in anoxic enviro...
The yeast-like fungus Aureobasidium thailandense LB01 produces a new biosurfact...
Meneses, D.; Gudiña, Eduardo J.; Fernandes, Fabiano; Gonçalves, Luciana R. B.; Rodrigues, L. R.; Rodrigues, SueliIn this study, the biosurfactant production by an Aureobasidium thailandense LB01 was reported for the first time. Different agro-industrial by-products (corn steep liquor, sugarcane molasses, and olive oil mill wastewater) were evaluated as alternative low-cost substrates. The composition of the culture medium was optimized through response surface methodology. The highest biosurfactant production (139 ± 16 mg...
Oxygenated monoterpenes-rich volatile oils as potential antifungal agents for d...
Dias, Nicolina; Dias, M. C.; Cavaleiro, C.; Sousa, M. C.; Lima, Nelson; Machado, M.Essential oils (EOs) extracted from Lavandula luisieri and Cymbopogon citratus were tested for their antifungal activity against ten clinical isolates of dermatophytes isolated from cases of tinea pedis. Inhibition of conidial germination and antifungal drug/EO combination assay were tested on two ATCC reference strains of Trichophyton rubrum and Trichophyton mentagrophytes. EOs were characterised by high amoun...
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